STUDIES ON PEPTIDES (Ⅵ)——SYNTHESIS AND PRIMARY BIOLOGICAL ACTIVITY EXAMINING OF THREE FRAGMENTS (93-102, 84-102, 25-38) OF TRANSFORMING GROWTH FACTOR-β  

作　　者：田少雷 蔡孟深 赵明 张肇康 

机构地区：[1]National Institutes of Pharmaceutical Research & Developmennt, Beijing 102206, PRC [2]Department of Peptide Research, School of Pharmaceutical Sciences. Beijing Medical University, Beijing 100083, PRC [3]Peninsula Laboratory Inc.Belmont CA 94002,USA

出　　处：《Chinese Science Bulletin》1992年第13期1116-1120,共5页

摘　　要：Transforming growth factor-β(TGF-β)is a multifunctional regulatory molecule existing in a wide variety of both normal and neoplastic cells. In order to evaluate the structure-function relationship of TGF-β, we have synthesized a series of its important fragments by manual stepwise solid-phase methodology and studied their biological activity. In

关 键 词：TRANSFORMING growth factor-β PEPTIDES SOLID-PHASE SYNTHESIS HPLC 

分 类 号：N[自然科学总论]