尿钙/肌酐比值预测妊娠高血压综合征的意义  

Value of Urinary Calcium/Creatinine Ratio in Prediction of Pregnancy-induced Hypertension

作　　者：张雪玉[1] 邹光珍 王东昌[1] 

机构地区：[1]宁夏医学院附属医院妇产科

出　　处：《宁夏医科大学学报》1992年第3期27-29,共3页Journal of Ningxia Medical University

摘　　要：测定127例子24～34周正常健康妇女的尿钙/肌酐比值,结果尿钙/肌酐比值≤0.049的41例,21例发生妊娠高血压综合征(妊高征),其敏感性、特异性、准确性、阳性及阴性预测值分别为58.33％、78.0295、72.44％、51.22％及82.56％。2～5周后该127例中有53例作了第二次测定,比值≤0.049约22例,17例发生了妊高征,其敏感性、特异性、准确性、阳性及阴性预测值分别为80.95％、84.38％、83.02%、72.27%及87.10%,均较前明显提高。尿钙/肌酐比值可作为预测妊高征的客观指标,连续动态观察价值更高。Uinary calcium(Ca^(2+))/creatinine (Cr) ratio was assayed in 127 normal healthy gravidae due 24～34 wks of gestation.Twenty-one of fourty-one cases in whom pregnancy-induced hypertension (PIH) developed later had a Ca^(2+)/Cr ratio≤0.049.The sensitivity, specificity, accuracy, positive predictive value &negative predictive value were 58.33%, 70.02%, 72.44%, 51.22% &82.56%, respectively.2 to 5 wks later, fifth-three of the 127 were checked again, the corresponding data ascended to 80.95%, 84.38%, 83.02%, 77.27% &87.10% respectively.Urinary Ca^(2+)/Cr ratio can bean useful screening index in predicting the consequent development of PIH. Dynamic observations of Ca^(2+)/Cr ratio posses still higher value.

关 键 词：妊娠高血压综合征 钙代谢障碍 肌酐 

分 类 号：R[医药卫生]