快中子治疗临床实验研究  

FAST NEUTRON TREATMENT OF CANCERS

作　　者：申文江 李庆琪[1] 鲍云华[2] 宋三泰[2] 刘辉[2] 陈国雄[3] 崔书祥[3] 泰康 崔广余 张红志 唐锦华[5] 常戚克 张仲伦[6] 罗醒萱[5] 张苏[5] 陈刚[5] 苏震[6] 谷铣之 殷蔚伯 曹逖闻 

机构地区：[1]北京市肿瘤研究所临床组,100034 [2]中国人民解放军307医院临床组,100039 [3]中国人民解放军总医院临床组,100853 [4]中国医学科学院肿瘤学院临床组,100021 [5]中国科学院高能物理研究所物理组,100039 [6]中国科学院生物物理研究所物理组,100080 [7]中国医学科学院肿瘤学院,100021

出　　处：《中华放射肿瘤学杂志》1992年第4期32-36,73,共6页Chinese Journal of Radiation Oncology

摘　　要：1991年11月到1992年2月在中国科学院高能物理研究所研制的快中子治癌装置上治疗10例恶性肿瘤患者,包括腮腺癌、颌下腺囊腺癌、成骨肉瘤、软骨肉瘤、前列腺癌、恶性黑色素瘤等。2例为术后放疗,8例为复发、远位转移的晚期病例。快中子照射剂量800ncGy/5f～2168ncGy/13f,2f/1wk。近期疗效CR5例,PR4例。有效率90％。副反应包括干、湿性脱皮、水泡、糜烂,7～20天内愈合。Ten patients with locally advanced cancers were treated with fast neutron at the Neutron Therapy Facility, The High-Energy Physics Institute, Chinese Academy of Sciences. There were 3 locally recurrent and lung metastases of adenoid cystic carcinoma of salivary gland, 2 osteosarcoma patients with lung metastases in one, 1 synoviosarcoma, 1 chondrosarcoma with lung metastases, 1 postatic cancer and 1 malignant melanoma. The doses ranged from 802 ncGy to 2168 ncGy. All treatments were given in 5 to 13 fractions over 14 to 45 days. Response was good in all. CR + PR was 90%. All showed early mild skin reactions without any severe sequalae.

关 键 词：肿瘤 放射治疗 快中子 

分 类 号：R73[医药卫生—肿瘤]