原发性肝癌与良性肝病血清唾液酸的研究  

STUDY OF SERLM SYALIC ACID IN PRIMARY HEPATIC CANCER AND HEPATIC BENIGN DISEASE

作　　者：刘金兰[1] 蔡至道[1] 沙文阁[1] 张岐山[2] 张玉魁[2] 潘忠诚[2] 王殿鸿[2] 张秀云[3] 

机构地区：[1]中国医科大学附属第一医院内科 [2]中国医科大学基础医学部 [3]沈阳市传染病院

出　　处：《中国医科大学学报》1992年第S1期79-81,共3页Journal of China Medical University

摘　　要：通过对原发性肝癌(PHC)、良性肝病及健康人血清唾液酸的研究表明:PHC患者血清唾液酸明显增高(2.969±0.677mmol/L),与良性肝病血清唾液酸(1.834±0.625mmol/L)相比,有显著差异(P<0.01),良性肝病与健康人血清唾液酸(1.543±0.433mmol/L)相比无显著差异(P>0.05)。血清唾液酸对PHC诊断的特异性为88.3％,敏感性为79.63％(P<0.01),尤其是对AFP阴性的PHC的阳性率为71.41％。血清唾液酸是PHC诊断和鉴别诊断的较好标志物之一。The serum sialic acid levels weie measured in 54 patients with primary hepatic canoer(PHC),64 hepatic benign disease, 6 metastatic hepatic carcinoma and 30 normal controls. It was found that the average value of sialic acid in PHC (2.969±0.677mmol/L) was significantly higher than that of the hepatic benign disease (1.834±0.625). However, it was not significant difference that the average value in hepatic benign disease conpared with that in halthy controls (1.543±0.433). Sensitivity and speciality of sialic acid to PHC were 79.63％, 88.30％.

关 键 词：原发性肝癌 良性肝病 唾液酸 

分 类 号：R[医药卫生]