正常宫颈粘膜及宫颈粘膜良、恶性病变的核仁组织形成区嗜银蛋白研究  

Study of AgNORs in cervix mucosa of normal and benign as well as malignant pathological changes

作　　者：缪智辉[1] 于桂芝[1] 殷平[2] 李丛仁 

机构地区：[1]牡丹江医学院附属一院妇产科 [2]哈尔滨医科大学

出　　处：《牡丹江医学院学报》1992年第1期7-8,共2页Journal of Mudanjiang Medical University

摘　　要：本文通过核仁组织形成区嗜银蛋白(AgNORs)染色技术对10例正常宫颈粘膜上皮及50例宫颈粘膜良、恶性病变进行研究,发现10例正常宫颈粘膜上皮的AgN。Rs计数为1.98±0.24/细胞。20例宫颈粘膜良性病变和30例鳞癌的AgNORs计数分别为2.01±0.32/细胞和4.20±0.32/细胞。结果表明正常宫颈粘膜上皮与宫颈粘膜良性病变的AgNORs计数无显著性差异(t=0.288,P>0.05),而正常宫颈粘膜上皮及宫颈粘膜良性病变与宫颈鳞癌的AgNORs计数有非常显著性差异(t=13.22P<0.001)。Using a sliver staining technique,nucleolar organizer region-associated proteins (Ag-NORs) have been studied in 10 cases of normal cervix mucosa and 50 cases of cervix mucosa of benign,malignant pathological changes.The research shows that the AgNORs numbers are 1.98+0.24/cell in 10 cases of normal cervix mucosa,and the AgNORs numbers are 2.01+0.32/cell and 4.20+0.30/cell respectively in 20 cases of cervix mucosa of benign pathological changes and 30 cases of cervix mucosa of squamous carcinoma. It turns out that there is no distinctive difference between the numbers of AgNoRs in cervix mucosa of nomal and that of benign pathological changes (t =0.288) (P>0.05) and the AgNORs numbers in cervix mucosa of squamous carcinoma are significantly different from the AgNORs numbers in cerix mucosa of normal and benign pathological change (t= 13.22, P<0.001) .

关 键 词：宫膜粘膜核仁组织形成区 嗜银蛋白 

分 类 号：R[医药卫生]