致密多晶羟基磷灰石人工骨修复外伤性下颌骨缺损的实验研究与临床应用  

EXPERIMENTAL STUDY AND CLINICAL APPLICATION OF REPAIR DEFECT OF MANDIBLE WITH DENSE POLYCRYTAL HYDROXYLAPATITE

作　　者：宋全衡[1] 钟庐云[1] 唐维平[1] 刘龙平[1] 张贤英[2] 

机构地区：[1]江西医学院第二附属医院,330006 [2]江西医学院解剖教研室

出　　处：《口腔颌面外科杂志》1992年第4期38-40,75,共4页Journal of Oral and Maxillofacial Surgery

摘　　要：作者通过11只家兔实验,经大体形态学、X线、光镜、电镜的观察表明人工骨植入兔下颌骨有良好的生物相容性,有骨引导作用,界面为骨性结合,与自体骨移植比较有类似的作用。临床上应用在外伤性骨缺损的8例,骨愈合良好,无排斥反应,是较理想的人工骨代用材料,实用于外伤性骨缺损的修复。22 transplanting operations were performed on two sides of mandibles of 11 rabbits, use dense polycrystal particulate hydroxylapatite were filled into defects of size 1.2×0.7cm^2, the specimens were collected in different period after operations. The observation was taken place under the general mophology, X-Ray, light microscope, and transfer electron microscope. The results indicated that HA have good biocompatibility and evidence indicated they have osteoconduction effect. Clinial appication 8 cases show that the dense polycrystal particulate hydroxylaptite is a quite ideal artificaiel bone. It has very good biocompatility, all patients are satisfied with the results.

关 键 词：羟基磷灰石 外伤 下颌骨 

分 类 号：R782[医药卫生—口腔医学]