肾脏疾病患者血中泌乳素、促黄体生成素、促卵泡刺激素及睾丸酮的改变  

The Variations of PRL, LH, FSH and Testosterone in Renal Disease

作　　者：田浩明[1] 梁荩忠[1] 马行一[2] 余庭龙 杨立川[2] 邱东生[3] 

机构地区：[1]华西医科大学内分泌科 [2]华西医科大学肾脏内科 [3]华西医科大学妇产科内分泌实验室

出　　处：《华西医科大学学报》1992年第1期94-97,共4页Journal of West China University of Medical Sciences

摘　　要：作者测定了41例不同程度肾功能损害的肾脏疾病患者(男22,女19)血清PRL水平,同时测定了男性患者的FSH,LH、T水平,并与20例同龄男性正常人PRL、LH、FSH、T水平进行了比较。结果发现肾脏疾病患者PRL水平升高,其中尿毒症期患者PRL升高显著。男性尿毒症患者除PRL水平明显升高外,LH也有升高,T水平则明显降低,且与肾功能损害程度有关。PRL水平与T水平呈负相关。5例男性尿毒症患者CAPD后未发现PRL、LH、FSH、T水平有明显变化。Blood PRL was measured withRIA in 22 males and 19 females with vari-ous degrees of renal insufficiency. At thesame time, blood LH, FSH, testosterone werestudied in all the male patients and 20 sex-age matched healthy subjects. The resultsshowed that the levels of PRL and LH wereincreased, and the level of testosterone wasdecreased significantly in male uremic pa-tients. There was a signifcant negative cor-relation between PRL and testosterone. All the above parameters were measur-ed again 8-25 days after continuous ambu-latory peritoneal dialysis (CAPD) therapyin 5 male uremic patients. The BUN and Crlevels decreased and the clinical manifes-tations of uremia improved. but the levelsof PRL, LH,FSH and testosterone showedno significant changes. The mechanisms ofthese variations were discussed.

关 键 词：尿毒症 泌乳素 促黄体生成素 促卵泡刺激素 睾丸酮 

分 类 号：R[医药卫生]