笼内换气对微环境的影响  

The Effect of Intra-cage Ventilation on Microenvironment

作　　者：程鸿[1] 杨幼明[1] 张帆[1] 

机构地区：[1]上海医科大学实验动物部

出　　处：《中国比较医学杂志》1991年第Z1期56-60,共5页Chinese Journal of Comparative Medicine

摘　　要：通过笼内氨浓度和垫料含水量的测试,判断一般鼠笼和载过滤帽鼠笼的气体交换情况,结果:在24～48h期间,带过滤帽鼠笼内氨浓度由45.64μg升至133.32μg,而笼内换气方式是53.1～16.67μg,垫料含水量增加情况与氨浓度变化相似。我们认为,过滤帽阻碍笼内外气体交换,导致笼内氨浓度和湿度明显升高。而笼内换气方式能改善动物所处的微环境,并减少笼与笼之间的干扰,便于清洗和易于操作是笼内换气工艺流程设计时应加以注意的问题。Four models of ventilation apparatus with 600 air changes per hour in each cabinet were designed and operated in experiment. The purpose of this study was to determine the efficiency of air exchanges in filter top covered cage ( A &B ) or in shoe box cage ( C &D ) , on the basis of ammonia ( NH3 ) level and excess moisture of the bedding. The results of tests to determine the NH3 level in cage A showed a significant increase during 24-48 hours. On the other hand, the excess water of bedding in cages, which was 4.5~7 times more that those in other cages, showed results similar to those observed in NH3 tests. We think that filter top cover resists air movement into the Micro-Isolater ( causing accumulation of NH3 and moisture in the cage). It suggests that intra-cage ventilation would improve the microenvironment and decrease cage to cage variability, but a resonable design of technological process for easy operating and cleaning should be noted.

关 键 词：微环境 笼内换气 氨浓度 

分 类 号：R[医药卫生]