Taq I RESTRICTION FRAGMENTS OF 21-OHase GENE IN CHINESE POPULATION  

作　　者：潘星时 陈磊 陈瑞冠 陈中孚 

机构地区：[1]Shanghai Institute for Pediatric Research, 1665 Kangjiang Road, Shanghai 200092, PRC [2]Institute of Genetics, Fudan University, Shanghai 200433, PRC

出　　处：《Chinese Science Bulletin》1991年第19期1671-1672,共2页

摘　　要：When blood DNA was digested with Taq I and monitored for RFLP with a human cDNA probe from the 21-hydroxylase genes (pC21/3c)in our laboratory, besides two characteristic restriction fragments 3.2 kb and 3.7 kb, an extra 5.6 kb band was revealed. This extra band appears both in normal Chinese individuals and in patients with congenital adrenal hyperplasia (CAH). The frequency is high (1/40 in phenotypically normal individuals and 1/18 in CAH patients). Evidently there is no selective pressure which is exerted

关 键 词：HYDROXYLASE CONGENITAL exerted monitored digested BESIDES ADRENAL DNA MENDEL Probe 

分 类 号：N[自然科学总论]