FORMATION OF SOLID PARTICLES IN BLOOD STREAM AND EFFECTS ON PULMONARY ULTRASTRUCTURE DURING CARDIOPULMONARY BYPASS IN CHILDREN  

作　　者：刘锦纷 苏肇伉 丁文祥 

机构地区：[1]Department of Pediatric Cardiothoracic Surgery, Xinhua Hospital, SSMU, Shanghai

出　　处：《Medical Bulletin of Shanghai Jiaotong University》1991年第1期58-65,共8页上海交通大学学报（医学英文版）

摘　　要：An electronic particle size analyzer (Coulter Counter ZM) was utilized to quantitate the particulate microemboli, varying from 15 to 80μin size, during cardiopulmonary bypass. We confirmed the main causes of microemboli were banked blood, cardiotomy reservoirs and oxygenators. Electronic microscopic examination showed that a large number of solid particles more than 20μin size were formed during heart-lung bypass, which obstructed microcirculation and damaged the pulmonary capillary endothelial and alveolar epithelial cells. The degree of histological damage was related to the number and size of microemboli and time of pulmonary microcirculatory obstruction.An electronic particle size analyzer (Coulter Counter ZM) was utilized to quantitate the particulate microemboli, varying from 15 to 80μ in size, during cardiopulmonary bypass. We confirmed the main causes of microemboli were banked blood, cardiotomy reservoirs and oxygenators. Electronic microscopic examination showed that a large number of solid particles more than 20μ in size were formed during heart-lung bypass, which obstructed microcirculation and damaged the pulmonary capillary endothelial and alveolar epithelial cells. The degree of histological damage was related to the number and size of microemboli and time of pulmonary microcirculatory obstruction.

关 键 词：CARDIOPULMONARY bypass (CPB) solid particle PULMONARY ULTRASTRUCTURE MICROEMBOLI 

分 类 号：R[医药卫生]