375例慢性脑出血后肺炎患者病原菌分布及其预后影响因素分析  

Pathogenic bacteria distribution and its prognostic factors of 375 pneumonia patients after chronic intracerebral hemorrhage

作　　者：王玉光[1] 孙兆家[2] 

机构地区：[1]山东省总工会青岛工人疗养院康复科,山东青岛266071 [2]青岛市立医院内科,山东青岛266011

出　　处：《中国生化药物杂志》2014年第2期157-159,共3页Chinese Journal of Biochemical Pharmaceutics

基　　金：青岛市科技局资助项目(042JZ96)

摘　　要：目的：探究并分析慢性脑出血后肺炎患者病原菌分布及其预后影响因素。方法选择山东省总工会青岛工人疗养院康复科2011年7月～2013年7月收治的375例慢性脑出血后肺炎患者为研究对象，分别采集痰液、血液和咽拭子进行细菌培养，直接免疫荧光法进行病毒检测，酶联免疫法进行非典型病原体检测，并采用自编问卷收集所有患者的临床资料，应用SPSS 17.0统计软件分析慢性脑出血后肺炎患者病原菌分布及其预后影响因素。结果慢性脑出血后肺炎患者预后良好率为85.60%，病原菌以细菌感染为主，占42.51%。多因素Logistic回归分析显示吞咽反射障碍(OR=12.922，P<0.01)和合并呼吸系统其他疾病(OR=3.327，P<0.01)是慢性脑出血后肺炎患者预后的危险因素，胸腹式呼吸训练(OR=0.695，P<0.01)是慢性脑出血后肺炎患者预后的保护因素。结论慢性脑出血后肺炎预后尚可，病原菌以革兰氏阴性杆菌感染为主，预后因素有吞咽反射障碍、合并呼吸系统其他疾病和胸腹式呼吸训，在临床医疗过程中，可加强胸腹式呼吸训指导，改善患者预后。Objective To explore and analyze the pathogenic bacteria distribution and its prognostic factors of pneumonia patients after chronic intracerebral hemorrhage. Methods 375 pneumonia patients after chronic intracerebral hemorrhage who were treated in the rehabilitation department of Qingdao Workers'' Sanatorium of Shandong Provincial Federation of Trade Unions from July 2011 to July 2013 were chosen as the research objects. The clinical data of all the subjects were collected, and the pathogenic bacteria distribution and its prognostic factors were analyzed by SPSS 17.0 statistical package. Results Good prognosis rate of the pneumonia patients after chronic intracerebral hemorrhage was 85.60%, the bacterium was the main pathogenic bacteria, accounted for 42.51%. Multiariable logistic regression analysis showed that swallowing reflex disorder (OR=12.922,P<0.01) and the combination of respiratory system disease (OR=3.327,P<0.01) were risk factors for the prognosis of pneumonia patients after chronic intracerebral hemorrhage, and chest breathing training (OR=0.695,P<0.01) was the protection factor. Conclusion The prognosis of pneumonia patients after chronic intracerebral hemorrhage is tolerable. The gram-negative bacterium is the main pathogenic bacteria. The prognostic factors of pneumonia patients after chronic intracerebral hemorrhage is concerned with swallowing reflex obstacles, other combination of respiratory system diseases and chest breathing training.In the process of clinical medical, we should strengthen the chest breathing training guidance and improve the prognosis of patients, especially in high-risk groups.

关 键 词：慢性脑出血后肺炎 病原菌 分布 预后影响因素 

分 类 号：R743.34[医药卫生—神经病学与精神病学]