Biofilms and Helicobacter pylori: Dissemination and persistence within the environment and host  

作　　者：Steven L Percival Louise Suleman 

机构地区：[1]Surface Science Research Centre and Institute of Ageing and Chronic Disease, University of Liverpool [2]Musculoskeletal Biology, Institute of Ageing and Chronic Disease, University of Liverpool

出　　处：《World Journal of Gastrointestinal Pathophysiology》2014年第3期122-132,共11页世界胃肠病理生理学杂志（英文版）（电子版）

摘　　要：The presence of viable Helicobacter pylori(H. pylori) in the environment is considered to contribute to the levels of H. pylori found in the human population, which also aids to increase its genetic variability and its environment adaptability and persistence. H. pylori form biofilms both within the in vitro and in vivo envi-ronment. This represents an important attribute that assists the survival of this bacterium within environ-ments that are both hostile and adverse to prolifera-tion. It is the aim of this paper to review the ability of H. pylori to form biofilms in vivo and in vitro and to address the inherent mechanisms considered to sig-nificantly enhance its persistence within the host and in external environments. Furthermore, the dissemi-nation of H. pylori in the external environment and within in the human body and its impact upon infec-tion control shall be discussed.The presence of viable Helicobacter pylori(H. pylori) in the environment is considered to contribute to the levels of H. pylori found in the human population, which also aids to increase its genetic variability and its environment adaptability and persistence. H. pylori form biofilms both within the in vitro and in vivo envi-ronment. This represents an important attribute that assists the survival of this bacterium within environ-ments that are both hostile and adverse to prolifera-tion. It is the aim of this paper to review the ability of H. pylori to form biofilms in vivo and in vitro and to address the inherent mechanisms considered to sig-nificantly enhance its persistence within the host and in external environments. Furthermore, the dissemi-nation of H. pylori in the external environment and within in the human body and its impact upon infec-tion control shall be discussed.

关 键 词：HELICOBACTER PYLORI Biofilm COCCOID forms VIRULENCE Water 

分 类 号：R573[医药卫生—消化系统]