Assessment of coronary artery disease using coronary computed tomography angiography and biochemical markers  

作　　者：Gitsios Gitsioudis Hugo A Katus Grigorios Korosoglou 

机构地区：[1]Department of Cardiology,University of Heidelberg

出　　处：《World Journal of Cardiology》2014年第7期663-670,共8页世界心脏病学杂志（英文版）（电子版）

摘　　要：Chronic inflammatory mechanisms in the arterial wall lead to atherosclerosis,and include endothelial cell damage,inflammation,apoptosis,lipoprotein deposition,calcification and fibrosis.Cardiac computed tomography angiography(CCTA)has been shown to be a promising tool for non-invasive assessment of theses specific compositional and structural changes in coronary arteries.This review focuses on the technical background of CCTA-based quantitative plaque characterization.Furthermore,we discuss the available evidence for CCTA-based plaque characterization and the potential role of CCTA for risk stratification of patients with coronary artery disease.Chronic inflammatory mechanisms in the arterial wall lead to atherosclerosis,and include endothelial cell damage,inflammation,apoptosis,lipoprotein deposition,calcification and fibrosis.Cardiac computed tomography angiography(CCTA)has been shown to be a promising tool for non-invasive assessment of theses specific compositional and structural changes in coronary arteries.This review focuses on the technical background of CCTA-based quantitative plaque characterization.Furthermore,we discuss the available evidence for CCTA-based plaque characterization and the potential role of CCTA for risk stratification of patients with coronary artery disease.

关 键 词：ATHEROSCLEROTIC PLAQUE composition Quantification analysis Multi-slice CARDIAC COMPUTED tomography Biomarkers 

分 类 号：R541.4[医药卫生—心血管疾病]