ATHEROSCLEROTIC

作品数：163被引量：489H指数：12
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Tanyu Tongzhi formula attenuates atherosclerotic plaque vulnerability by inhibiting CD40^(+) monocyte differentiation
《Traditional Medicine Research》2025年第4期61-71,共11页Zheng-Tian Lv Yan-Yun Pan Chen-Xia Wu Yuan-Gang Qiu Shen-Jie Chen Wei Mao Jin Dai 
Natural Science Foundation of Zhejiang Province(grant number LY20H290005);Key Research and Development Program of Zhejiang Province(grant number 2020C03119);National Natural Science Foundation of China(grant numbers 81673706,81973579,82174150);Science and Technology Program of Zhejiang Traditional Chinese Medicine(grant number 2018ZY005);TCM science and Technology Foundation Project of Zhejiang Province(grant number 2023ZL411).
Background:Atherosclerosis(AS)is a chronic progressive inflammatory disease,and plaque stability plays a critical role in preventing acute events.Tanyu Tongzhi formula(TTF),a traditional Chinese medicine,has potential...
关键词：ATHEROSCLEROSIS Tanyu Tongzhi formula CD40^(+)monocyte differentiation inflammation 
Lipid levels and insulin resistance markers in patients with colorectal cancer:Propensity score matching analysis
《World Journal of Gastrointestinal Oncology》2025年第1期130-142,共13页Ren-Hao Hu Dong-Yi Yan Ke-Hui Zhang Di Zhang Xi-Mao Cui Xiao-Hua Jiang Shun Zhang 
Supported by Pudong New Area Science and Technology Development Fund for Livelihood Research Special Project,No.PKJ2023-Y38.
BACKGROUND Colorectal cancer(CRC)is a prevalent malignant neoplasm characterized by subtle early manifestations.AIM To investigate the correlation among serum lipid profiles,the triglyceride-glucose(TyG)index,and the ...
关键词：Colorectal cancer Serum lipids Triglyceride-glucose index Atherosclerotic index Diagnostic marker 
Inhibition of the RXRA-PPARα-FABP4 signaling pathway alleviates vascular cellular aging by an SGLT2 inhibitor in an atherosclerotic mice model
《Science China(Life Sciences)》2024年第12期2678-2691,共14页Weiwei Zhang Linghuan Wang Yujia Wang Yan Fang Ruihua Cao Zhiyi Fang Dong Han Xu Huang Zhenghui Gu Yingjie Zhang Yan Zhu Yan Ma Feng Cao 
supported by the National Key Research and Development Projects (2022YFC3602400);the National Natural Science Foundation of China (92249301,82200496);Project of National Clinical Research Center for Geriatric Diseases (NCRCGPLAGH-2022001)。
Atherosclerosis is the pathological cause of atherosclerotic cardiovascular disease(ASCVD),which rapidly progresses during the cellular senescence.Sodium-glucose cotransporter 2 inhibitors(SGLT2is)reduce major cardiov...
关键词：ATHEROSCLEROSIS cellular senescence SGLT2 inhibitors PPARΑ 
Urolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E–deficient mice
《Acta Pharmacologica Sinica》2024年第11期2277-2289,共13页Meng-yun Xu Jing-jing Xu Li-jing Kang Zheng-hong Liu Mei-ming Su Wen-qi Zhao Zhi-hua Wang Lu Sun Jian-bo Xiao Paul C.Evans Xiao-yu Tian Li Wang Yu Huang Xin-miao Liang Jian-ping Weng Suo-wen Xu 
supported by grants from the National Key R&D Program of China(Grant No.2021YFC2500500);the National Natural Science Foundation of China(Grant No.82370444,82070464,82003741);the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB38010100);supported by the Program for Innovative Research Team of The First Affiliated Hospital of USTC(CXGG02);Anhui Provincial Key Research and Development Program(Grant No.202104j07020051);Anhui Provincial Natural Science Foundation(Grant No.2208085J08).
Urolithin A(UroA),a dietary phytochemical,is produced by gut bacteria from fruits rich in natural polyphenols ellagitannins(ETs).The efficiency of ETs metabolism to UroA in humans depends on gut microbiota.UroA has sh...
关键词：atherosclerosis urolithin A INFLAMMATION YAP/TAZ endothelial cells 
Improving a Patient’s CVD Risk Assessment—Updating the Interpretation of the Lipid Profile
《World Journal of Cardiovascular Diseases》2024年第9期515-520,共6页David S. Schade Allen Adolphe Robert Philip Eaton 
The lipid profile remains an important laboratory assessment to prevent cardiovascular disease. Interpretation of the non-fasting lipid profile has significantly changed based on new information concerning the pathoge...
关键词：Lipid Profile Atherosclerotic Risk Cardiovascular Disease High Density Lipoprotein Low Density Lipoprotein 
Mediating function of heart failure in the causal relationship between diastolic blood pressure and hypertensive renal disease with renal failure:a mediated Mendelian randomization study
《Frontiers of Nursing》2024年第3期285-294,共10页Lei Pang Zi-Jun Ding Hong-Qiang Chai Fei Li Ming Wu Wei-Bing Shuang 
supported by the scientific research project of Shanxi Provincial Health Commission(No.2022073)。
Objective:To study the causality relationship between diastolic blood pressure(DBP)and hypertensive renal disease with renal failure(HRDRF)and the mediating role of hear t failure(HF)in the causality relationship by n...
关键词：atherosclerotic heart disease diastolic blood pressure heart arrhythmia heart failure hypertensive renal disease with renal failure Mendelian randomization 
Hemorrhagic transformation in patients with large-artery atherosclerotic stroke is associated with the gut microbiota and lipopolysaccharide被引量：1
《Neural Regeneration Research》2024年第7期1532-1540,共9页Qin Huang Minping Wei Xianjing Feng Yunfang Luo Yunhai Liu Jian Xia 
supported by the National Key Research and Development Projects,Nos.2022 YFC3602400,2022 YFC3602401(to JX);the Project Program of National Clinical Research Center for Geriatric Disorders(Xiangya Hospital),No.2020LNJJ16(to JX);the National Natural Science Foundation of China,No.82271369(to JX)。
Hemorrhagic transformation is a major complication of large-artery atheroscle rotic stroke(a major ischemic stro ke subtype)that wo rsens outcomes and increases mortality.Disruption of the gut microbiota is an importa...
关键词：gut microbiota hemorrhagic transformation INFLAMMATION LIPOPOLYSACCHARIDE STROKE 
Effects of Lizhong Tongmai acupuncture on TMAO,CD36 expression,and cholesterol deposition in atherosclerotic mice
《China Medical Abstracts(Internal Medicine)》2024年第2期72-73,共2页孙瑞 
Objective To observe the effects of Lizhong Tongmai acupuncture(acupuncture for regulating middle jiao and promoting meridians)on trimethylamine-N-oxide(TMAO),CD36 expression,and cholesterol deposition in atherosclero...
关键词：CD36 ACUPUNCTURE CHOLESTEROL 
YKL40 potentially via activating the P38 pathway in decreasing atherosclerotic plaque stability
《Chinese Medical Journal》2024年第8期1003-1005,共3页Chao Wang Yandong Liu Wei Huan Jianjin Wu Jie Jin Sili Zou Yu Chen Lefeng Qu 
Specifically Invited Professor of Oriental Scholar of Shanghai Colleges and Universities Tracking Program(No.GZ2016008);National Natural Science Foundation of China(No.81870347)
To the Editor:Atherosclerosis is the main pathological feature of ischemic stroke,which remains a major cause of disability and death worldwide.[1]Vulnerable plaque,was characterized by ulceration,platelet activation,...
关键词：YKL40 markedly STABILITY 
Metabolite acetyl-L-carnitine participates in Bifidobacterium animalis F1-7 to ameliorate atherosclerotic inflammation by downregulating theTLR4/NF-κB pathway
《Food Science and Human Wellness》2024年第2期813-822,共10页Xi Liang Zhe Zhang Xiaoying Tian Qingyu Cui Haiyan Lu Maozhen Zhao Tongjie Liu Huaxi Yi Pimin Gong Lanwei Zhang 
supported by Shandong Taishan industry leading talent project(LJNY202101);the National Key R&D of China(2018YFC0311201)。
This study aimed to explore the effect of Bifidobacterium animalis F1-7 on the improvement of atherosclerotic inflammation.Arteriosclerosis model ApoE^(-/-)mice were orally administered with B.animalis F1-7 for 12 wee...
关键词：Bifidobacterium animalis F1-7 Atherosclerosis INFLAMMATION METABONOMICS ACETYL-L-CARNITINE 
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