METABONOMICS

作品数：102被引量：383H指数：11
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The intestinal microbiota and metabolic profiles of Strauchbufo raddei underwent adaptive changes during hibernation被引量：1
《Integrative Zoology》2024年第4期612-630,共19页Hanwen CAO Yongpeng SHI Ji WANG Zhanyu NIU Li WEI Huabing TIAN Feifei YU Lan GAO 
supported by the National Natural Science Foundation of China(Grant No.31471953).
The intestinal microbiota help regulate hibernation in vertebrates.However,it needs to be established how hibernation modulates the gut microbiome and intestinal metabolism.In the present study,we used an artificial h...
关键词：biomakers HIBERNATION intestinal microbiota METABONOMICS Strauchbufo raddei 
Research on the Orientated Effective Components of Huangqi in Huangqi Jianzhong Tang Against Chronic Atrophic Gastritis Based on Multi-Spectrum–Effect Correlation
《World Journal of Traditional Chinese Medicine》2024年第2期244-253,共10页Guo-Hong Wang Long-Fei Yang Shi-Wei Wang Yue-Tao Liu 
Objective: This study aimed to investigate the orientated effective components of Astragali Radix Huangqi(HQ) in HQ Jianzhong Tang(HQJZ), a classical formula of traditional Chinese medicine(TCM) used for treating chro...
关键词：Astragali radix chronic atrophic gastritis Huangqi Jianzhong Tang METABONOMICS spectrum–effect relationship 
Metabolite acetyl-L-carnitine participates in Bifidobacterium animalis F1-7 to ameliorate atherosclerotic inflammation by downregulating theTLR4/NF-κB pathway
《Food Science and Human Wellness》2024年第2期813-822,共10页Xi Liang Zhe Zhang Xiaoying Tian Qingyu Cui Haiyan Lu Maozhen Zhao Tongjie Liu Huaxi Yi Pimin Gong Lanwei Zhang 
supported by Shandong Taishan industry leading talent project(LJNY202101);the National Key R&D of China(2018YFC0311201)。
This study aimed to explore the effect of Bifidobacterium animalis F1-7 on the improvement of atherosclerotic inflammation.Arteriosclerosis model ApoE^(-/-)mice were orally administered with B.animalis F1-7 for 12 wee...
关键词：Bifidobacterium animalis F1-7 Atherosclerosis INFLAMMATION METABONOMICS ACETYL-L-CARNITINE 
Effect of Rhei Radix et Rhizoma and Eupolyphaga Steleophaga on liver protection mechanism based on pharmacokinetics and metabonomics
《Chinese Herbal Medicines》2024年第1期121-131,共11页Gang Feng Jianli Bi Wenfang Jin Qi Wang Zhaokui Dan Baolei Fan 
supported by the Key R&D Plan of Hubei Province for local special support in the field of general health(No.2022BCE066).
Objective:Based on metabonomics technology of high-performance liquid chromatography-mass spectrometry(HPLC-MS/MS)and hydrogen nuclear magnetic resonance spectroscopy(^(1)H NMR),the pharmacokinetic characteristics and...
关键词：Dahuang Zhechong Pills Eupolyphaga Steleophaga 1H NMR HPLC-MS/MS METABONOMICS PHARMACOKINETICS Rhei Radix et Rhizoma 
Microbial phenolic metabolites 3-(3',4'-dihydroxyphenyl)propanoic acid and 3',4'-dihydroxyphenylacetic acid prevent obesity in mice fed high-fat diet被引量：2
《Food Science and Human Wellness》2024年第1期327-338,共12页Wanbing Chen Ruonan Liu Xiaoling Zhu Qun Lu Hong Yang Rui Liu 
supported by the project of the National Natural Science Foundation of China(32272331);the project of Fundamental Research Funds for the Central Universities(2662019PY034)。
Obesity is associated with numerous metabolic disorders,and dietary polyphenols have been confirmed to have beneficial effects on the metabolism in obesity.However,the effect of 3-(3’,4’-dihydroxyphenyl)propanoic ac...
关键词：OBESITY Dietary polyphenol metabolites Gut microbiota METABONOMICS 
Plasma Metabonomics of Human Adenovirus-infected Patients with Pneumonia and Upper Respiratory Tract Infection
《Current Medical Science》2024年第1期121-133,共13页Ting-ting WEI Wen XU Bo TU Wan-xue ZHANG Xin-xin YANG Yiguo ZHOU Shan-shan ZHANG Jun-lian YANG Ming-zhu XIE Juan DU Wei-wei CHEN Qing-bin LU 
supported by the National Natural Science Foundation of China(No.82073617);Joint Research Fund for Beijing Natural Science Foundation and Haidian Original Innovation(No.L202007);Fundamental Research Funds for the Central Universities and Peking University Health Science Center(No.BMU2021YJ041);Peking University Medicine Fund of Fostering Young Scholars'Scientific&Technological Innovation(No.BMU2021PY005).
Objective Human adenovirus(HAdV)infection is common and can develop to serious conditions with high mortality,yet the mechanism of HAdV infection remains unclear.In the present study,the serum metabolite profiles of H...
关键词：human adenovirus metabonomic LIPIDS PNEUMONIA upper respiratory tract infection 
Quercetin Attenuates Atherosclerosis via Modulating Apelin Signaling Pathway Based on Plasma Metabolomics被引量：4
《Chinese Journal of Integrative Medicine》2023年第12期1121-1132,共12页LIU Li-qun ZHANG Peng QI Ying-zi LI Hui JIANG Yue-hua YANG Chuan-hua 
Supported by Shandong Province'Taishan Scholar'Construction Project Funds (No.2018-35)。
Objective:To interpret the pharmacology of quercetin in treatment of atherosclerosis(AS).Methods:Fourteen apolipoprotein E-deficient(ApoE^(-/-))mice were divided into 2 groups by a random number table:an AS model(ApoE...
关键词：QUERCETIN ATHEROSCLEROSIS plasma metabonomics apelin signaling pathway 
Stachyose modulates gut microbiota and alleviates DSS-induced ulcerative colitis in mice被引量：1
《Food Science and Human Wellness》2023年第6期2211-2220,共10页Chen Wang Junying Bai Botao Wang Leilei Yu Fengwei Tian Jianxin Zhao Hao Zhang Huayi Suo Wei Chen Qixiao Zhai 
Stachyose is a prebiotic that traditionally extracted from plants,such as vegetable.It has been demonstrated to alleviate intestinal inflammation by regulating gut microbiota,but the mechanism has been unclear.This re...
关键词：STACHYOSE Prebiotic COLITIS METABONOMICS Gut microbiota 
The efficacy and mechanism of fecal microflora transplantation in the treatment of slow transit constipation based on metabonomics anion mode
《Microenvironment & Microecology Research》2023年第3期1-9,共9页Lu Han Chen Xu Hai-Zhao Liu Yi-Yang Wang Lu-Lu Xie Yu-Wei Li Yu-Tong Jin Jia-Tong Liu Ji-Da Wang Joseph Kofi Abankwah Yu-Hong Bian 
National Key R&D Program of China(No.2018YFC1706506);Foundation of Tianjin Municipal Health Commission(No.ZC20097);Foundation of Tianjin Union Medical Center(No.2020YJ017,2017YJZD005);National Natural Science Foundation of China(No.82174374);College of Integrated Traditional Chinese and Western Medicine,Tianjin University of Traditional Chinese Medicine 2021 Postgraduate Innovation Fund(No.ZXYCXLX202115).
Background:Fecal microbiota transplantation(FMT)based on the positive ion mode of metabonomics has a good therapeutic benefit for slow transit constipation(STC)patients.However,a piece of comprehensive metabolomics in...
关键词：Fecal microbiota transplantation Slow transit constipation metabolomics anion mode LACTOBACILLUS 
Heat stroke alters hippocampal and cerebellar transmitter metabonomics被引量：3
《World Journal of Emergency Medicine》2023年第4期287-293,共7页Guoxin He Ancong Xu Xichong Yu Fan Huang Lei Su 
supported by the grants from Zhejiang Provincial Natural Science Foundation(LGF19H150004);Zhejiang Provincial Medical Science and Technology project(2022RC258)。
BACKGROUND:The mechanisms underlying heat stroke(HS)-induced hippocampal injury remain unclear.This study aimed to evaluate the HS-induced metabonomics of hippocampal and cerebellar transmitters.METHODS:The HS model w...
关键词：Heat stroke Transmitters Rat HIPPOCAMPUS CEREBELLUM METABONOMICS 
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