ACETYL-L-CARNITINE

作品数：11被引量：12H指数：2
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相关领域：医药卫生更多>>
相关作者：王建枝更多>>
相关机构：华中科技大学台湾大学更多>>
相关期刊：《国际眼科杂志》《Reproductive and Developmental Medicine》《World Journal of Gastroenterology》《Neural Regeneration Research》更多>>
相关基金：湖北省自然科学基金国家自然科学基金更多>>
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Effect of acetyl L-carnitine on human retinal pigment epithelium-19 cells in hypoxic conditions
《国际眼科杂志》2024年第10期1515-1521,共7页Ali Dal Onur Catak Murat Erdag Mehmet Canleblebici Ebru Onalan Ilay Buran 
Firat大学科研中心项目(No.TF:19.41)。
AIM:To investigate the effect of acetyl-L-carnitine(ALCAR)on cell viability,morphological integrity,and vascular endothelial growth factor(VEGF)expression in human retinal pigment epithelium(ARPE-19)cells using a hypo...
关键词：acetyl-L-carnitine(ALCAR) human retinal pigment epithelium(ARPE-19) vascular endothelial growth factor(VEGF) hypoxia-inducible factor 1(HIF-1α) 
Metabolite acetyl-L-carnitine participates in Bifidobacterium animalis F1-7 to ameliorate atherosclerotic inflammation by downregulating theTLR4/NF-κB pathway
《Food Science and Human Wellness》2024年第2期813-822,共10页Xi Liang Zhe Zhang Xiaoying Tian Qingyu Cui Haiyan Lu Maozhen Zhao Tongjie Liu Huaxi Yi Pimin Gong Lanwei Zhang 
supported by Shandong Taishan industry leading talent project(LJNY202101);the National Key R&D of China(2018YFC0311201)。
This study aimed to explore the effect of Bifidobacterium animalis F1-7 on the improvement of atherosclerotic inflammation.Arteriosclerosis model ApoE^(-/-)mice were orally administered with B.animalis F1-7 for 12 wee...
关键词：Bifidobacterium animalis F1-7 Atherosclerosis INFLAMMATION METABONOMICS ACETYL-L-CARNITINE 
Effect of acetyl-L-carnitine on hypersensitivity in acute recurrent caerulein-induced pancreatitis and microglial activation along the brain’s pain circuitry被引量：4
《World Journal of Gastroenterology》2021年第9期794-814,共21页Sabrina L McIlwrath Marlene E Starr Abigail E High Hiroshi Saito Karin N Westlund 
United States Department of Veterans Affairs,VA Merit Grant,No.BX002695;United States National Institute of Health,No.R01AG055359,No.R01GM126181 and No.R01NS39041-15.
BACKGROUND Acute pancreatitis(AP)and recurring AP are serious health care problems causing excruciating pain and potentially lethal outcomes due to sepsis.The validated caerulein-(CAE)induced mouse model of acute/recu...
关键词：Acute recurrent pancreatitis Neuropathic pain Mechanical hypersensitivity Heat hypersensitivity Anxiety-like behavior Ionized calcium-binding adaptor molecule 1 
Acetyl-L-carnitine protects adipose-derived stem cells exposed to H2O2 through regulating AMBRA1-related autophagy
《BIOCELL》2021年第1期189-198,共10页YAO QIAN JINGPING WANG ZIWAN JI HAO CHEN YUCANG HE XULING LV ZIKAI ZHANG TIAN LI TIANYUN PAN LIQUN LI MING LIN 
funded by the National Natural Science Foundation of China[grant no.81971850];a grant from the Municipal Science and Technology Bureau of Wenzhou[2018Y0383,2019Y0538].
The cell activity of adipose-derived stem cells(ADSCs)is affected by the intracellular reactive oxygen species(ROS)and the level of autophagy.Previous studies reveal that acetyl-L-carnitine(ALC)possesses capacities of...
关键词：Oxidative stress Cell activity Autophagy-related proteins Antioxidant enzymes 
Supplementation with L-Carnitine Rescues Sperm Epigenetic Changes in Asthenospermic Male Semen with Altered Acetyl-L-Carnitine Levels
《Reproductive and Developmental Medicine》2020年第3期146-155,共10页Xiao-Hui Jiang Chuan Jiang Lin Yu Xiao-Liang Li Tao Zuo Pei-Fei Gu Fu-Ping Li Wen-Ming Xu 
funded by the National Key Research and Development Program of China(SQ2018YFC1003603);the Natural Science fund of Liaoning Province(project number:201601424);the Northeast Pharmaceutical Group Co.,Ltd(NEPG).
Objective:To investigate the relationship between the concentration of L-carnitine in semen and sperm parameters and investigate the epigenetic profile in sperm cell after L-carnitine usage.Methods:From February 2017 ...
关键词：ACETYL-L-CARNITINE ASTHENOSPERMIA EPIGENETIC Sperm DNA Damage 
Effect of Specific Nutrients on Ovulation, Oocytes Development, Gene Expression and Coupling Success in Mice
《International Journal of Clinical Medicine》2018年第9期660-674,共15页P. Vitullo C. Cossetti M. A. Virmani 
Introduction: The roles of genetic, epigenetic, metabolic and other environmental factors such as nutrition and stress, are becoming evident for a successful and healthy pregnancy. This raises the possibility and ques...
关键词：Pregnancy L-CARNITINE ACETYL-L-CARNITINE MICRONUTRIENTS OOCYTES Birth Fetal Health Embryos Key Genes Fertilization REPRODUCTIVE 
Treatment with acetyl-L-carnitine exerts a neuroprotective effect in the sciatic nerve following loose ligation:a functional and microanatomical study被引量：1
《Neural Regeneration Research》2018年第4期692-698,共7页Daniele Tomassoni Lorenzo Di Cesare Mannelli Vincenzo Bramanti Carla Ghelardini Francesco Amenta Alessandra Pacini 
funded by the Italian Ministry of Instruction,University and Research(MIUR);the Universities of Florence and Camerino
Peripheral neuropathies are chronic painful syndromes characterized by allodynia,hyperalgesia and altered nerve functionality.Nerve tissue degeneration represents the microanatomical correlate of peripheral neuropathi...
关键词：peripheral nerve chronic constriction injury neurorestoration morphology NEUROFILAMENT myelin basic protein neural regeneration 
Acetyl-L-carnitine:An Effective Antioxidant against Cryo-damage on Human Spermatozoa with Asthenospermia被引量：7
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2017年第6期915-921,共7页邹宇洁 杨菁 常硕 徐望明 尹太郎 龙文 
supported by grants from the Natural Science Foundation of Hubei Province(No.2016CFB352);Hubei Province Health and Family Planning Scientific Research Project(No.WJ2017M011);China Scholarship Council(No.201706275124)
A variety of natural and artificial cryoprotectant extenders have been explored to enhance sperm recovery following cryopreservation-thawing process. The current investigation is aimed at evaluating the effect of acet...
关键词：acetyl-L-carnitine human spermatozoa DNA damage acrosome integrity 
The Possible Mechanisms Involved in the Protection Strategies against Radiation-Induced Cellular Damage by Carnitines
《International Journal of Clinical Medicine》2015年第2期71-80,共10页Ashraf Virmani Andreas Diedenhofen 
There is constant low level background radiation from the cosmos but in certain situation the body may be subjected to increased acute or chronic exposure from other sources. This occurs in situations such as radiatio...
关键词：Radiation L-CARNITINE ACETYL-L-CARNITINE ANTIOXIDANTS MITOCHONDRIA DNA 
Behaviour and Degenerative Changes in the Basal Forebrain Systems of Aged Rats (12 Months Old) after Levo-Acetyl-Carnitine Treatments
《Journal of Behavioral and Brain Science》2012年第1期18-25,共8页Roberta Freddi Piergiorgio Duca Maurizio Mariotti Ivana Gritti 
One group of six male control rats [12 months old] and one group of six male rats of the same age, singularly maintained in a cage, and treated with acetyl-L-carnitine-HCl [(gamma-trimethyl-beta-acetyl-butyrobetaine-H...
关键词：Acetyl-L-Carnitine-HCl Ageing CHOLINE ACETYLTRANSFERASE Neurons Substantia Innominata MORRIS Maze-Water Task 
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