ACETYLTRANSFERASE

作品数：31被引量：42H指数：4
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相关领域：医药卫生生物学更多>>
相关作者：刘琳钟建铭鲁莹张雅慧王艳丽更多>>
相关机构：中国科学技术大学温州医科大学内蒙古科技大学中国科学院更多>>
相关期刊：《Science China(Life Sciences)》《Virologica Sinica》《Chinese Medical Journal》《Genes & Diseases》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划王宽诚敎育基金更多>>
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A comprehensive and systematic analysis of Dihydrolipoamide S-acetyltransferase (DLAT) as a novel prognostic biomarker in pan-cancer and glioma
《Oncology Research》2024年第12期1903-1919,共17页HUI ZHOU ZHENGYU YU# JING XU ZHONGWANG WANG YALI TAO JINJIN WANG PEIPEI YANG JINRONG YANG TING NIU 
supported by Achievement Transformation Project(No.CGZH21001);1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(No.ZYJC21007);Translational Research Grant of NCRCH(No.2021WWB03);Chengdu Science and Technology Program(No.2022-YF05-01444-SN);Key Research and Development Program of Sichuan Province(No.2023YFS0031);National Key Research and Development Program of China(Nos.2022YFC2502600,2022YFC2502603);National Natural Science Foundation of China(No.82370192).
Background:Dihydrolipoamide S-acetyltransferase(DLAT)is a subunit of the pyruvate dehydrogenase complex(PDC),a rate-limiting enzyme complex,that can participate in either glycolysis or the tricarboxylic acid cycle(TCA...
关键词：Dihydrolipoamide S-acetyltransferase(DLAT) GLIOMA PROGNOSTIC IMMUNOLOGICAL 
Shi-pi-xiao-ji formula suppresses hepatocellular carcinoma by reducing cellular stiffness through upregulation of acetyl-coA acetyltransferase 1
《World Journal of Gastrointestinal Oncology》2024年第6期2727-2741,共15页Hui-Ying Jian Zi-Cheng Liang Huan Wen Zhen Zhang Pu-Hua Zeng 
Supported by the National Natural Science Foundation of China,No.82074425;Hunan Science and Technology Planning Project,No.2016SK2051 and No.2023SK2057;the Hunan Provincial Administration of Traditional Chinese Medicine Research Project,No.B2023089.
BACKGROUND Previous studies have shown that the Shi-pi-xiao-ji(SPXJ)herbal decoction formula is effective in suppressing hepatocellular carcinoma(HCC),but the underlying mechanisms are not known.Therefore,this study i...
关键词：Shi-pi-xiao-ji formula Hepatocellular carcinoma Cellular stiffness Plasma membrane cholesterol level AcetylcoA acetyltransferase 1 
ATAT1 deficiency enhances microglia/macrophage-mediated erythrophagocytosis and hematoma absorption following intracerebral hemorrhage
《Neural Regeneration Research》2024年第5期1072-1077,共6页Yihua Zhang Ping Huang Min Cao Yi Chen Xinhu Zhao Xuzhi He Lunshan Xu 
supported by Science and Technology Innovation Enhancement Project of Army Medical University(to LX).
MIcroglia/macrophage-mediated erythrophagocytosis plays a crucial role in hematoma clearance after intracerebral hemorrhage.Dynamic cytoskeletal changes accompany phagocytosis.However,whether and how these changes are...
关键词：acetylatedα-tubulin α-tubulin acetyltransferase 1(ATAT1) erythrophagocytosis hematoma absorption intracerebral hemorrhage MACROPHAGE MICROGLIA 
ACAT1 deficiency in myeloid cells promotes glioblastoma progression by enhancing the accumulation of myeloid-derived suppressor cells被引量：1
《Acta Pharmaceutica Sinica B》2023年第12期4733-4747,共15页Mingjin Wang Weida Wang Shen You Zhenyan Hou Ming Ji Nina Xue Tingting Du Xiaoguang Chen Jing Jin 
supported by National Key R&D Program of China(No.2019YFE0111800);National Natural Science Foundation of China(Nos.T2192972,81872923,and 81903904);the CAMS Innovation Fund(2022-I2M-1-014,China).
Glioblastoma(GBM)is a highly aggressive and lethal brain tumor with an immunosuppressive tumor microenvironment(TME).In this environment,myeloid cells,such as myeloid-derived suppressor cells(MDSCs),play a pivotal rol...
关键词：GLIOBLASTOMA Myeloid cells Myeloid-derived suppressor cells Acetyl-CoA acetyltransferase 1 CXCL1 Tumor microenvironment Lipid metabolism MACROPHAGES 
A recently evolved BAHD acetyltransferase,responsible for bitter soyasaponin A production,is indispensable for soybean seed germination被引量：2
《Journal of Integrative Plant Biology》2023年第11期2490-2504,共15页Jia Yuan Liya Ma Yan Wang Xindan Xu Rui Zhang Chengyuan Wang Wenxiang Meng Zhixi Tian Yihua Zhou Guodong Wang 
financially supported by National Key Research and Development Projects (2021YFF1001200 and 2018YFA0900603);“Priority Research Program”of the Chinese Academy of Science (Grant No.ZDRW-ZS-2019-2);the State Key Laboratory of Plant Genomics of China (SKLPG2016A-13)to GW。
Soyasaponins are major small molecules that accumulate in soybean(Glycine max)seeds.Among them,type-A soyasaponins,fully acetylated at the terminal sugar of their C22 sugar chain,are responsible for the bitter taste o...
关键词：BAHD acyltransferase seed germination SOYASAPONIN soybean 
MZF1(Myeloid Zinc Finger 1)activates transcriptional activity of p53 and suppresses breast cancer cell proliferation via acetyltransferase PCAF(P300/CBP associated factor)
《Genes & Diseases》2023年第5期1775-1778,共4页Bowen Li Shujing Li Xiaoxia Shi Yini Zhang Zhiqiang Xin Yuxi Yang Binggong Zhao Ping Ren Huijian Wu 
supported by grants(No.81872263 to H.W.)from the National Natural Science Foundation of China.
p53 is an important tumor suppressor gene.The p53 pathway is activated in response to cellular stress stimulation.However,in more than 50%of breast cancers,p53 is mutated or inactivated,which permits cancer growth.1 A...
关键词：SCAN Zinc P53 
Acetyltransferase P300 Inhibits the Proliferation, Invasion, and Migration of Esophageal Cancer via Survivin Acetylation
《Chinese Medicine》2022年第4期51-65,共15页Jingxiong Zheng Jingtao Huang Zongying Liang 
Background: Esophageal cancer is one of the primary death causes leading by cancer in the world, which is high morbidity and mortality. Epigenetic acetylation modification participates in and regulates the proliferati...
关键词：P300 ACETYLTRANSFERASE SURVIVIN Acetylation Modification Esophageal Cancer 
Direct acetylation of a conserved threonine of RIN4 by the bacterial effector HopZ5 or AvrBsT activates RPM1-dependent immunity in Arabidopsis被引量：5
《Molecular Plant》2021年第11期1951-1960,共10页Arabidopsis Sera Choi Maxim Prokchorchik Hyeonjung Lee Ravi Gupta Yoonyoung Lee Eui-Hwan Chung Buhyeon Cho Min-Sung Kim Sun Tae Kim Kee Hoon Sohn 
This research was supported by Basic Science Research Programs through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(NRF-2019R1I1A1A01060108);Korean government(MSIT)(NRF-2018R1A5A1023599 and NRF-2019R1A2C2084705)。
Plant pathogenic bacteria deliver effectors into plant cells to suppress immunity and promote pathogen survival;however, these effectors can be recognised by plant disease resistance (R) proteins to activate innate im...
关键词：Acetyltransferase effectors Effector-triggered immunity Immunity suppressors NLR Plant deacetylase Plant immunity 
Characterization of a Membrane-Bound O-Acetyltransferase Involved in Trioxacarcin Biosynthesis Offers Insights into Its Catalytic Mechanism被引量：1
《Chinese Journal of Chemistry》2020年第12期1607-1611,共5页Yue Yin Yi Shen Song Meng Mei Zhang Hai-Xue Pan Gong-Li Tang 
We thank the supporting grants from the NNSFC(Nos.21632007 and 21621002);the CAS(No.XDB20000000 and K.c.wong Education Foundation).
of main observation and conclusion Trioxacarcin A(TXN-A)is a polycyclic aromatic natural product with remarkable biological activity.TxnB11,a membrane-bound O-acetyltransferase involved in TXN-A biosynthesis that is d...
关键词：utilize CATALYTIC ANALOGS 
Submicroscopic 11p13 deletion including the elongator acetyltransferase complex subunit 4 gene in a girl with language failure, intellectual disability and congenital malformations: A case report
《World Journal of Clinical Cases》2020年第21期5296-5303,共8页Jaime Toral-Lopez Luz María González Huerta Olga Messina-Baas Sergio A Cuevas-Covarrubias 
Supported by PAEP,2018 and PAPIIT IN219419,DGAPA,Universidad Nacional Autónoma de México,No.IN219419.
BACKGROUND We described the main features of an infant diagnosed with facial dysmorphic,language failure,intellectual disability and congenital malformations to strengthen our understanding of the disease.Currently,tr...
关键词：Submicroscopic 11p13 deletion Elongator acetyltransferase complex subunit 4 gene Language failure Intellectual disability Congenital malformations Case report 
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