supported by Fundação de AmparoàPesquisa do Estado do Rio de Janeiro(FAPERJ,E-26/010.002160/2019,E-26/203.227/2017,E-260003/001177/2020,and E-26/201.279/2021);Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq,313757/2020-8,311188/2023-0)(to PMPC).
Neonatal hypoxic-ischemic encephalopathy(HIE)is a significant cause of disability in children.Improving brain function and accelerating neurological recovery may require a combination of neuroprotective and pro-regene...
Supported by Natural Science Foundation of Henan Province,No.242300421286;the research and practice project of higher education reform in Henan Province,No.2023SJGLX124Y;the research and practice project of higher education reform of Zhengzhou University,No.2023ZZUJGXM114.
BACKGROUND Early symptoms of hepatocellular carcinoma(HCC)are not obvious,and more than 70%of which does not receive radical hepatectomy,when first diagnosed.In recent years,molecular-targeted drugs combined with immu...
Supported by the National Natural Science Foundation of China:81173342;Scientific Research Ability Improvement Projects of Hebei College of Traditional Chinese Medicine(now known as Hebei University of Chinese Medicine):KTZ2019012;Scientific Research Project of Hebei Province Administration of Traditional Chinese Medicine:2022361.2021095。
Objective:The preventive and therapeutic effects of direct moxibustion on a gastric cancer rat model induced by the intragastric administration of N-methyl-N’-nitro-N-nitrosoguanidine(MNNG)were evaluated.Changes in t...
supported by the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(2019PT310029);Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(2023-I2M-2-001);the National Natural Science Foundation of China(82161148009);the Fundamental Research Funds for the Central Universities(3332021092);the Strategic Priority Research Program of Chinese Academy of Sciences(grant no.XDB38030400);the Key Collaborative Research Program of the Alliance of International Science Organizations(ANSO-CR-KP-2022-09).
The gut microbiota undergoes substantial changes in COVID-19 patients;yet,the utility of these alterations as prognostic biomarkers at the time of hospital admission,and its correlation with immunological and hematolo...
supported by Beijing Science and Technology Commission(grant number Z211100002921059);National Science and Technology Major Projects of China(2017ZX10201201-001-006,2017ZX10201201-002-006,and 2018ZX10715-005-003-005);Digestive Medical Coordinated Development Center of Beijing Hospital Authority(XXZ0302 and XXT28);National Key R&D Program China(2022YFC2603505);Beijing Hospital Authority Clinical Medicine Development with Special Funding Support(XMLX 202127);High-Level Public Health Technical Personnel Training Program of Beijing the Municipal Health Commission(2022-3-050);Capital Health Research and Development of Special(2022-1-2172).
Objective Hepatocellular carcinoma(HCC)is sensitive to ferroptosis,a new form of programmed cell death that occurs in most tumor types.However,the mechanism through which ferroptosis modulates HCC remains unclear.This...
supported by the NationalNatural Science Foundation of China(no.32360888);the Jiangxi Students’Platform for Innovation and Entrepreneurship Training Program(no.202411843023).
Background:Heat shock protein B8(HSPB8)is implicated in autophagy,and its aberrant expression has been linked to both the ini-tiation and progression of tumors.However,the role and function of HSPB8 in colorectal canc...
Supported by National Natural Science Foundation of China,No.82270632 and No.82260411.
BACKGROUND Hepatic alveolar echinococcosis(HAE)is a chronic parasitic disease caused by the larval stage of Echinococcus multilocularis.Although significant research has been conducted on the pathogenesis and immunolo...
National Natural Science Foundation of China(No.NSFC82372331);Project of Science and Technology Department of Sichuan Province(Nos.2024NSFSC1551 and 2023NSFSC0716)
To the Editor:Immune checkpoint inhibitors(ICIs)have shown remarkable clinical responses;however,their efficacy remains limited to a small subset of patients.Peripheral blood mononuclear cells(PBMCs)offer an effective...
FACCE-JPI program and received funding from the German Federal Ministry of Food and Agriculture(BMEL)through the Federal Office for Agriculture and Food(BLE,Bonn,Germany),grant number 2814ERA04A;the epimural microbiome analysis was financially supported the FBN seed funding program.
The milk replacer feeding regime in dairy calves has a great impact on metabolic and immunological functioning and affects animal welfare and lifetime performance.The feeding regime influences the rumen microbial comp...
supported by the National Natural Science Foundation of China,China (No.81970016,81870039).
The immune responses play a profound role in the progression of lung lesions in both infectious and non-infectious diseases.Dendritic cells,as the"frontline"immune cells responsible for antigen presentation,set up a b...