Immunological landscape of hepatic alveolar echinococcosis: A bibliometric analysis  

作　　者：Aliya Tulading Jing Wu Yun-Fei Zhang Alimujiang Mamuti Yilizhati Azhati Chun-Hui Lv Abudusalamu Tuersunmaimaiti Tuerhongjiang Tuxun 

机构地区：[1]Department of Liver&Laparoscopic Surgery,Center of Digestive and Vascular Surgery,First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,Xinjiang Uygur Autonomous Region,China

出　　处：《World Journal of Hepatology》2025年第2期238-250,共13页世界肝病学杂志(英文)

基　　金：Supported by National Natural Science Foundation of China,No.82270632 and No.82260411.

摘　　要：BACKGROUND Hepatic alveolar echinococcosis(HAE)is a chronic parasitic disease caused by the larval stage of Echinococcus multilocularis.Although significant research has been conducted on the pathogenesis and immunological aspects of HAE,comprehensive bibliometric analyses in this area are still lacking.This study sought to fill this gap by systematically analyzing the immunological literature on HAE using bibliometric methods.AIM To identify research trends,key contributors,and emerging developments and offer insights to guide future research in this field.METHODS Research articles on HAE published between 1983 and 2023 were retrieved from the Web of Science Core Collection database.A total of 319 articles were selected for bibliometric analysis,which was conducted using the CiteSpace and VOSviewer software.The analysis focused on key variables such as publication volume,authors,journals,countries,references,and keywords.RESULTS The analysis revealed a significant increase in research on HAE over the past four decades,particularly after 1995.China and Switzerland emerged as the leading countries in terms of publication volume,with Bruno Gottstein and Vuitton DA identified as the most influential authors in this field.Key research areas include the interaction between the pathogen and the host immune system,as well as advances in disease diagnosis and treatment strategies.The keyword co-occurrence analysis highlighted the primary themes and identified emerging trends within the research landscape.CONCLUSION This study provides a comprehensive framework for understanding HAE immunology and highlights research hotspots,future directions,key contributors,and the importance of international cooperation.

关 键 词：Hepatic alveolar echinococcosis IMMUNE BIBLIOMETRICS VISUALIZATION CITESPACE Vosviewer 

分 类 号：R532.3[医药卫生—内科学] G353.1[医药卫生—临床医学]