National Natural Science Foundation of China(Grant Nos.32070838 and 82301874);Open Fund of State Key Laboratory of Reproductive Medicine,Nanjing Medical University(Grant No.SKLRM K202102)。
Meiotic resumption in mammalian oocytes involves nuclear and organelle structural changes,notably the chromatin configuration transition from a non-surrounding nucleolus(NSN)to surrounding nucleolus(SN)in germinal ves...
supported by the National Key Research and Development Program of China(2021YFC2700100);the Natural Science Foundation of Zhejiang Province(LD22C060001);the National Natural Science Foundation of China(31930031);the fellowship of China National Postdoctoral Program for Innovative Talents(BX20230031);Beijing Natural Science Foundation(7244435).
Proper ovarian follicle development,which is required for the maintenance of female fertility,is critical for the production of mature oocytes[1,2].Meanwhile,the correct establishment of the epitranscriptome in oocyte...
supported by the grants from the National Key R&D Program of China(Nos.2022YFA1303301 and 2021YFA1100201);the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB0570000);the National Natural Science Foundation of China(Nos.31970607 and 31470781 to L.W.,No.32200696 to H.Z.);the China Postdoctoral Science Foundation(No.2021M700146 to H.Z.);the Heye Scholarship(to X.L.).
PIWI-interacting RNAs(piRNAs),which associate with PIWI clade Argonaute proteins to form piRNA-induced silencing complexes(piRISCs)in germline cells,are responsible for maintaining genomic integrity and reproductive f...
The study was carried out within the"Priority-2030"program project(Priority-2030 Grant,Samara State Medical University,Ministry of Health of Russia).
Nowadays,assisted reproductive technologies are becoming increasingly in demand in people’s lives and activities.One of the most important stages of assisted reproductive technology is the cultivation of oocytes and ...
supported by the National Key R&D Program of China(Grant Nos.2019YFA0110000 and 2021YFA1100300);the National Natural Science Foundation of China(Grant Nos.31972882,31721003,31771419,and 31900621);the Natural Science Foundation of Shanghai Municipality,China(Grant No.21ZR1465500)。
The development and maturation of follicles is a sophisticated and multistage process.The dynamic gene expression of oocytes and their surrounding somatic cells and the dialogs between these cells are critical to this...
National Natural Science Foundation of China (No.82072880,81960283);Science and Technology Project of Hainan Province (No.LCYX202102);Key Science and Technology Project of Hainan Province (No.ZDKJ2017007)。
With the clinical development and application of intracytoplasmic sperm injection(ICSI)technology in human assisted reproduction,the influence of oocyte quality on embryo development has been paid more and more attent...
Supported by LUO Yuankai Research Fund for Young Scholars(No.20190810);National Natural Science Foundation of China(No.82174429)。
Objective:To explore the effects of Zishen Yutai Pills(ZYPs)on the quality of oocytes and embryos,as well as pregnancy outcomes in patients with diminished ovarian reserve(DOR)receiving in vitro fertilizationembryo tr...
supported by grants from the National Natural Science Foundation of China(32022018 and 31871360 to J.Gao)。
Reproductive aging is a natural process conserved across species and is well-known in females.It shows age-related follicle depletion and reduction of oocyte quality,eventually causing reproductive senescence and meno...
performed within the framework of State projects 122041100276-0 and 075-01027-2200。
Reproduction technologies(RTs)can provide for the reliable reproduction of amphibians,as well as perpetuation of species genetic variation with the use of biobanks.In 1982,in anticipation of the biodiversity conservat...
the National Natural Science Foundation of China(Nos.11627803,32061160475,and 11872355).
The beginning of a mammalian life commences with a fertilized oocyte.The study of oocytes is certainly one of the most intriguing scientific questions of our time.Herein,we studied oocytes from a mechanical perspectiv...