The study was carried out within the"Priority-2030"program project(Priority-2030 Grant,Samara State Medical University,Ministry of Health of Russia).
Nowadays,assisted reproductive technologies are becoming increasingly in demand in people’s lives and activities.One of the most important stages of assisted reproductive technology is the cultivation of oocytes and ...
supported by the National Key R&D Program of China(Grant Nos.2019YFA0110000 and 2021YFA1100300);the National Natural Science Foundation of China(Grant Nos.31972882,31721003,31771419,and 31900621);the Natural Science Foundation of Shanghai Municipality,China(Grant No.21ZR1465500)。
The development and maturation of follicles is a sophisticated and multistage process.The dynamic gene expression of oocytes and their surrounding somatic cells and the dialogs between these cells are critical to this...
National Natural Science Foundation of China (No.82072880,81960283);Science and Technology Project of Hainan Province (No.LCYX202102);Key Science and Technology Project of Hainan Province (No.ZDKJ2017007)。
With the clinical development and application of intracytoplasmic sperm injection(ICSI)technology in human assisted reproduction,the influence of oocyte quality on embryo development has been paid more and more attent...
Supported by LUO Yuankai Research Fund for Young Scholars(No.20190810);National Natural Science Foundation of China(No.82174429)。
Objective:To explore the effects of Zishen Yutai Pills(ZYPs)on the quality of oocytes and embryos,as well as pregnancy outcomes in patients with diminished ovarian reserve(DOR)receiving in vitro fertilizationembryo tr...
supported by grants from the National Natural Science Foundation of China(32022018 and 31871360 to J.Gao)。
Reproductive aging is a natural process conserved across species and is well-known in females.It shows age-related follicle depletion and reduction of oocyte quality,eventually causing reproductive senescence and meno...
performed within the framework of State projects 122041100276-0 and 075-01027-2200。
Reproduction technologies(RTs)can provide for the reliable reproduction of amphibians,as well as perpetuation of species genetic variation with the use of biobanks.In 1982,in anticipation of the biodiversity conservat...
the National Natural Science Foundation of China(Nos.11627803,32061160475,and 11872355).
The beginning of a mammalian life commences with a fertilized oocyte.The study of oocytes is certainly one of the most intriguing scientific questions of our time.Herein,we studied oocytes from a mechanical perspectiv...
National Key Research and Development Program Topics,Grant/Award Number:2021YFD1200402;Chinese Universities Scientific Fund,Grant/Award Number:2021TC061;Natural Science Foundation of Hebei province,Grant/Award Number:H2020206254;Special Program for Training and Guiding Outstanding Young and Middle-aged Talents,Grant/Award Number:SKLSGIHP2021A01;National Natural Science Foundation of China,Grant/Award Number:81901562&31372307;Key research and development projects in Hebei province,Grant/Award Number:18226604D;Program of Young and Middle-aged Scientific and technological Innovation Leaders of the Xinjiang Production and Construction Corps,Grant/Award Number:2018CB025;Xinghuo program of the First Hospital of Hebei Medical University,Grant/Award Number:XH202005;The Central Guidance on Local Science and Technology Development Fund of Hebei Province,Grant/Award Number:226Z7713G。
Background:Irreversible cryodamage caused by oocyte vitrification limited its wild application in female fertility preservation.Antioxidants were always used to antagonist the oxidative stress caused by vitrification....
Ministry of Science and Technology of China,National Key R&D Program of China(No.2017YFC1002003 and No.2017YFC1001601)
Objective:The purpose of this study was to evaluate the sperm motility and DNA integrity at different temperatures to analyze whether the sperms are suitable on the second day for insemination of in vitro matured oocy...
the National Key Research and Development Program of China(2021YFC2700400 to Q.W.);the National Natural Science Foundation of China(81925014 to Q.W.;31900594to L.H.;81872650to M.C.);the Natural Science Foundation of Jiangsu Province(BK20190615 to L.H.).
Mitochondria are essential for female reproductive processes,yet the function of mitochondrial DNA(mtDNA)mutation in oocytes remains elusive.By employing an mtDNA mutator(Polgm)mouse model,we found the fetal growth re...