supported by the National Key R&D Program of China(2023YFC2705503);Major Innovation Projects in Shandong Province(2021ZDSYS16);the National Natural Science Foundation of China(82071699 and 82371619);CAMS Innovation Fund for Medical Sciences(2021-I2M-5-001);the Basic Science Center Program of NSFC(31988101);Science Foundation for Distinguished Young Scholars of Shandong(ZR2021JQ27);Taishan Scholars Program for Young Experts of Shandong Province(tsqn202103192)。
Non-obstructive azoospermia(NOA),the lack of sperm in the ejaculate due to failure of spermatogenesis,can result from a variety of diverse factors,with genetic factors accounting for~30%of NOA cases,including chromoso...
This study was funded by grants from the Zhejiang Province Traditional Chinese Medicine Science and Technology Project(2023ZL056);the Foundation Project of Zhejiang Chinese Medical University(2022JKJNTZ16).
Background:Piwi-interacting RNAs(piRNAs)are a type of non-coding RNAs,initially identified in germ cells in 2006,known to bind to the Piwi family proteins.Accumulating studies indicate their importance in genome stabi...