TRANSPOSON

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Advances in PIWI-piRNA function in female reproduction in mammals被引量：1
《Acta Biochimica et Biophysica Sinica》2025年第1期148-156,共9页Xiaolong Lv Hongdao Zhang Ligang Wu 
supported by the grants from the National Key R&D Program of China(Nos.2022YFA1303301 and 2021YFA1100201);the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB0570000);the National Natural Science Foundation of China(Nos.31970607 and 31470781 to L.W.,No.32200696 to H.Z.);the China Postdoctoral Science Foundation(No.2021M700146 to H.Z.);the Heye Scholarship(to X.L.).
PIWI-interacting RNAs(piRNAs),which associate with PIWI clade Argonaute proteins to form piRNA-induced silencing complexes(piRISCs)in germline cells,are responsible for maintaining genomic integrity and reproductive f...
关键词：PIRNA PIWI TRANSPOSON OOCYTES FERTILITY 
Core factor of NEXT complex,ZCCHC8,governs the silencing of LINE1 during spermatogenesis
《National Science Review》2025年第1期37-47,共11页Rushuang Yan Meijie Qi Pengfei Zhang Bin Shen Jiqing Yin Chuan Chen Silin Tian Lin Chen Xingxu Huang Hong Wang Shaorong Gao You Wu Yawei Gao 
supported by the National Key R&D Program of China(2020YFA0113200[Y.G.],2021YFC2700300[S.G.]and 2022YFC2702200[S.G.]);the National Natural Science Foundation of China(32370869[Y.G.],32330030[S.G.],92168205[S.G.],32200694[Y.W],82301859[M.Q.]);Peak Disciplines(Type IV)of Institutions of Higher Learning in Shanghai(S.G.),Young Elite Scientists Sponsorship Program by CAST(2023QNRC001[Y.W]);the key project of the Science and Technology of Shanghai Municipality(21JC1405500[S.G.]);the Shanghai Rising-Star Program(22YF1436200[Y.W.]);the Shanghai Pilot Program for Basic Research(Y.G.),Special Fund for Health Science and Technology of Social Development Shanghai Pudong New Area(PKJ2022-Y20)(L.C.);Fundamental Research Funds for the Central Universities and the China Postdoctoral Science Foundation(2023M733267[P.Z.]).
The overactivation of transposable elements(TEs)is a significant threat to male reproduction,particularly during the delicate process of spermatogenesis.Here,we report that zinc finger protein ZCCHC8-a key component o...
关键词：transposon elements nuclear exosome targeting complex LINE1 spermatogonial stem cells SPERMATOGENESIS 
Regulation of human interferon signaling by transposon exonization
《四川生理科学杂志》2024年第12期2607-2607,共1页Giulia Irene Maria Pasquesi 
Innate immune signaling is essential for clearing pathogens and damaged cells and must be tightly regulated to avoid excessive inflammation or autoimmunity.Here,we found that the alternative splicing of exons derived ...
关键词：controlling DECOY finding 
The evolutionary tale of lilies:Giant genomes derived from transposon insertions and polyploidization被引量：1
《The Innovation》2024年第6期41-43,共3页Sujuan Xu Runzhou Chen Xinqi Zhang Yufeng Wu Liuyan Yang Zongyi Sun Zhitao Zhu Aiping Song Ze Wu Ting Li Biao Jin Shihui Niu Xin-Cheng Huang Si-Jie Liu Cheng-Ao Yang Guixia Jia Yanhong He Fang Du Minmin Chen Fei Chen Wenhe Wang Hongmei Sun Yongyao Fu Weibiao Liao Huaidi Pei Xuewei Wu Sixiang Zheng Jia-Yu Xue Guogui Ning Ray Ming Nianjun Teng 
supported by the National Key R&D Program of China(grant no.2019YFD1000400);the“JBGS”Project of Seed Industry Revitalization in Jiangsu Province(JBGS[2021]093);the Project for Crop Germplasm Resources Conservation of Jiangsu Province(grant no.2021-SJ-011);the Seed Industry Innovation Project(2021NK1005)from the Department of Science and Technology of Hunan Province;the High-level Key Discipline Construction Project for Traditional Chinese Medicine-Resources Science of Chinese Medicinal Materials from National Administration of Traditional Chinese Medicine;the Fundamental Research Funds for the Central Universities from Nanjing Agricultural University;the Pilot Incubation Project of Modern Flower and Horticultural Industry Technology from Nanjing Oriole Island Modern Agricultural Development Co.,Ltd;This work was supported by the high-performance computing platformof Bioinformatics Center,Nanjing Agricultural University.
Dear Editor,Lily(Lilium spp.),known as the“king of bulbous flowers,”has high ornamental and medicinal value due to its attractive,fragrant flowers and nutritious bulbs.The Lilium genus comprises approximately 115 pe...
关键词：spp flowers insertion 
Genome editing in plants using the TnpB transposase system被引量：1
《aBIOTECH》2024年第2期225-230,共6页Qi Li Yongqiang Wang Zhuoting Hou Hang Zong Xuping Wang Yong EZhang Haoyi Wang Haitao Chen Wen Wang Kang Duan 
The widely used clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated nuclease(Cas)system is thought to have evolved from IS200/IS605 transposons.TnpB proteins,encoded by one type of IS20...
关键词：ISAam1 ISDra2 ISYmu1 Plant genome editing Rice TnpB transposon endonuclease 
Improvement in Tol2 transposon for efficient large-cargo capacity transgene applications in cultured cells and zebrafish(Danio rerio)被引量：1
《Zoological Research》2024年第3期567-574,共8页Peng-Cheng Wang Hao Deng Rang Xu Jiu-Lin Du Rongkun Tao 
supported by the National Science and Technology Innovation 2030 Major Projects(2021ZD0202200);National Natural Science Foundation of China(32171090,81970264);Shanghai Science and Technology Commission(21ZR1482600);2023 Youth Innovation Promotion Association CAS。
Most viruses and transposons serve as effective carriers for the introduction of foreign DNA up to 11 kb into vertebrate genomes.However,their activity markedly diminishes with payloads exceeding 11 kb.Expanding the p...
关键词：ZEBRAFISH Tol2 transposase TRANSGENE Large payload Synthetic biology 
Cas9-targeted Nanopore sequencing rapidly elucidates the transposition preferences and DNA methylation profiles of mobile elements in plants
《Journal of Integrative Plant Biology》2023年第10期2242-2261,共20页Pavel Merkulov Sofya Gvaramiya Maxim Dudnikov Roman Komakhin Murad Omarov Alina Kocheshkova Zakhar Konstantinov Alexander Soloviev Gennady Karlov Mikhail Divashuk Ilya Kirov 
supported by the Russian Science Foundation (grant no. 20-74-10055;RNA-seq and mobilome analyses of plants after heat stress);Kurchatov Genomic Center of All-Russia Research Institute of Agricultural Biotechnology (agreement no. 075-15-20191667;CANS development)。
Transposable element insertions(TEIs) are an important source of genomic innovation by contributing to plant adaptation, speciation, and the production of new varieties. The often large,complex plant genomes make iden...
关键词：Arabidopsis DNA methylation Nanopore sequencing transposon insertions 
Cell division factor ZapE regulates Pseudomonas aeruginosa biofilm formation by impacting the pqs quorum sensing system
《mLife》2023年第1期28-42,共15页Xi Liu Minlu Jia Jing Wang Hang Cheng Zhao Cai Zhaoxiao Yu Yang Liu Luyan ZMa Lianhui Zhang Yingdan Zhang Liang Yang 
supported by the Guangdong Natural Science Foundation for Distinguished Young Scholar(2020B1515020003);Shenzhen Science and Technology Program KQTD20200909113758004;China Postdoctoral Science Foundation(2020M672649);National Natural Science Foundation of China(91951204 and 32200155);Guangdong Basic and Applied Basic Research Foundation(2019A1515110640 and 2020A1515010316).
Pseudomonas aeruginosa is one of the leading nosocomial pathogens that causes both severe acute and chronic infections.The strong capacity of P.aeruginosa to form biofilms can dramatically increase its antibiotic resi...
关键词：BIOFILM Pseudomonas aeruginosa Pseudomonas quinolone signal transposon‐insertion site sequencing(Tn‐seq) ZapE 
Robust genome and RNA editing via CRISPR nucleases in PiggyBac systems
《Bioactive Materials》2022年第8期313-320,共8页Yuqian Jiang Rachel Catherine Hoenisch Yun Chang Xiaoping Bao Craig E.Cameron Xiaojun Lance Lian 
supported by NIH R21EB026035(X.L.L.);NIH R21AI149312(C.E.C.,and X.L.L.);NSF CBET-1943696(X.L.L.);Penn State startup funding to X.L.L.
CRISPR/Cas-mediated genome editing in human pluripotent stem cells(hPSCs)offers unprecedented opportunities for developing in vitro disease modeling,drug screening and cell-based therapies.To efficiently deliver the C...
关键词：CRISPR-Cas9 Genome editing Cas13d RNA editing PiggyBac transposon Human pluripotent stem cells 
Functional characterization of piggyBac-like elements from Nilaparvata lugens(St?l)(Hemiptera:Delphacidae)被引量：1
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2022年第6期515-527,共13页Jun LYU Qin SU Jinhui LIU Lin CHEN Jiawei SUN Wenqing ZHANG 
the Foundation of Guangzhou Science and Technology Key Project(No.201904020041),China。
Piggy Bac is a transposable DNA element originally discovered in the cabbage looper moth(Trichoplusia ni).The T.ni piggyBac transposon can introduce exogenous fragments into a genome,constructing a transgenic organism...
关键词：Nilaparvata lugens piggyBac-like elements TRANSPOSON NlPLE25 
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