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financially supported by grants to Y.H.Y.from the Natural Science Foundation of Guangxi Zhuang Autonomous Region(2019GXNSFFA245013,2018GXNSFDA050017);the National Natural Science Foundation of China(81871172);the Guangxi Medical University Training Program for Distinguished Young Scholars.This review was also supported by Special Fund of the Female Fertility Preservation Innovation Team of the First Affiliated Hospital of Guangxi Medical University.
The female ovaries are critical for follicle growth and development in the process known as"folliculogenesis".This complex process is regulated by various factors,among which the microenvironment around follicles appe...
supported by the National Key R&D Program of China(Grant Nos.2019YFA0110000 and 2021YFA1100300);the National Natural Science Foundation of China(Grant Nos.31972882,31721003,31771419,and 31900621);the Natural Science Foundation of Shanghai Municipality,China(Grant No.21ZR1465500)。
The development and maturation of follicles is a sophisticated and multistage process.The dynamic gene expression of oocytes and their surrounding somatic cells and the dialogs between these cells are critical to this...
supported by the grants from the Science and Technology Program of Guangzhou,China(No.201904010041);the Guangdong Basic and Applied Basic Research Foundation(No.2020A1515010033);the National Natural Science Foundation of China(No.30900232);the Guangdong Science and Technology Department Foundation(No.2020B1212060031);the Research Grant of Key Laboratory of Regenerative Medicine,Ministry of Education,Jinan University(No.ZSYXM202207).
Obesity has been reported to promote disordered folliculogenesis,but the exact molecular mechanisms are still not fully understood.In this study,we find that miR-133a is involved in obesity-induced follicular developm...
supported by Xuzhou Medical University start-up grant for excellent scientists (Nos. RC20552044, RC20552054);the Natural Science Research of the Jiangsu Higher Education Institutions (Nos. 21KJB330007, 21KJB320001)。
2,6-Dichloro-1,4-benzoquinone(2,6-DCBQ), an emerging water disinfection by-product, is widely detected in water resources. However, its potential effects on the reproductive system are largely unknown. Here, we invest...
This research was supported by TETFUND-IBR and TETFUNDAST&D with reference number UN/VC/T/19/N.2.
Objective:To evaluate the development of ovarian follicles in female albino rats following vitamin D3 supplementation.Methods:Eighteen prepubertal female albino rats,aged 3-4 weeks,weighing(70.25±9.16)g,were assigned...
supported by the USDA-ARS Biophotonics(Grant#58–6402–3-018);the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior–Brasil(CAPES)–Finance Code 001.VM Paes is the recipient of a PhD scholarship from CAPES。
Background:Ovarian follicular fluid influences follicle and oocyte growth,but the fluctuation of its protein content during folliculogenesis has not been comprehensively analyzed.Here we used a shotgun approach and bi...
supported by grants from the National Key R&D Program of China(2018YFC1003700,2018YFC1003800,and 2017YFC1001100);the National Natural Science Foundation of China(31872792,31371448,and 31571540);Beijing Natural Science Foundation(5182015 and 7182090);Project of State Key Laboratory of Agrobiotechnology(2015SKLAB4-1 and 2016SKLAB-1);Institution of Higher Education Projects of Building First-class Discipline Construction in Ningxia Region(NXYLXK2017B05).
Establishment of the primordial follicle(PF)pool is pivotal for the female reproductive lifespan;however,the mechanism of primordial folliculogenesis is poorly understood.Here,the transcription factor SP1 was shown to...
Heat stress is identified as a major cause of lower productive and reproductive performance in animal farming. This situation is more common in Saudi Arabia than in other countries because of extremely high ambient te...
Objectives: Evaluating the addition effect of./. insularis extract and FSH on the survival, activation and ROS production after in vitro culture of ovine preantral follicles enclosed in ovarian tissue. Methods: In t...
Understanding the mechanisms of human germ cell biology is important for developing infertility treatments. However, little is known about the mechanisms that regulate human gametogenesis due to the difficulties in co...