Lucentis联合氪黄激光治疗视网膜分支静脉阻塞黄斑水肿的疗效观察  

Lucentis with laser photocoagulation for macular edema in BRVO

作　　者：张祺[1] 冯劼[1] 李培凤[1] 金翼[1] 

机构地区：[1]武汉市第一医院眼科,湖北省武汉市430033

出　　处：《眼科新进展》2013年第12期1148-1149,共2页Recent Advances in Ophthalmology

摘　　要：目的评价Lucentis联合氪黄激光治疗视网膜分支静脉阻塞黄斑水肿的疗效和安全性。方法将40例(40眼)视网膜分支静脉阻塞合并黄斑水肿的患者随机分为A、B两组,A组接受单纯黄斑格栅激光治疗,B组接受单次Lucentis玻璃体注射7 d后联合黄斑格栅光凝治疗。随访6个月,对比2组患者治疗后最佳矫正视力和黄斑中心厚度。结果随访期末,B组最佳矫正视力提高11例(55%),A组最佳矫正视力提高2例(10%),2组差异有统计学意义(P<0.05)。治疗后1周、6个月2组黄斑中心厚度分别为(419.6±105.0)μm和(320.1±102.0)μm、(328.8±95.0)μm和(198.2±86.0)μm,组间相比,差异均有统计学意义(均为P<0.05)。结论 Lucentis联合氪黄激光治疗视网膜分支静脉阻塞黄斑水肿是一种比传统单纯激光治疗更安全、有效的方法。Objective To evaluate the efficacy and safety of lucentis with laser photocoagulation for macular edema in branch retinal vein occlusion(BRVO).Methods Forty eyes of 40 patients with macular edema secondary to BRVO were randomized into two groups: Group A received grid laser treatment alone group B received the laser photocoagulation at 7 days after intravitreal injection of lucentis.The best corrected visual acuity and central macular thickness were measured at 6 months.Results At 6 months,the best corrected visual acuity in group A and B improved in 2 eyes(10%)and 11 eyes(55%)(P<0.05).The central macular thickness at postoperative 1 week and 6 months were(419.6±105.0)μm,(320.1± 102.0)μmin group A,(328.8±95.0)μm,(198.2±86.0)μmin group B(all P<0.05). Conclusion Lucentis with grid laser photocoagulation for macular edema is more safety and effective than traditional single photocoagulation.

关 键 词：LUCENTIS 黄斑水肿 视网膜分支静脉阻塞 

分 类 号：R779.63[医药卫生—眼科]