ACA与脑出血患者病情的相关性分析  

Correlation analysis of ACA and condition of patients with cerebral hemorrhage

作　　者：黄丽云[1] 巫翠萍[1] 

机构地区：[1]海南医学院附属医院检验科,海口570102

出　　处：《中国实用神经疾病杂志》2013年第17期27-28,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的分析抗心磷脂抗体(ACA)与脑出血患者病情的相关性。方法选取我院自2007—2010年收治的确诊为脑出血患者80例,将其作为临床研究对象设为观察组,选取64例在年龄、性别等方面与患者相近的健康检查者,将其设为对照组。应用酶联免疫吸附法(ELISA)分别于脑出血病人发病1d、2周时测定ACA的水平,并用CT测量血肿的量、分析ACA与脑出血患者病情的关系。结果观察组ACA阳性率36.25%远大于对照组的9.38%,2组相差26.87%。将观察组中进一步分成血肿扩大组和血肿不变组,前者的ACA阳性率65.52%与后者的ACA阳性率19.61%相比,相差45.91%。进一步研究观察组发病1d时ACA阳性率与2周时ACA阳性率相比,相差16.25%,P<0.05,差异具有统计学意义。结论 ACA阳性率高低对脑出血患者病情的诊断具有重要作用。Objective To analyze the correlation between ACA and the disease condition of patients with cerebral hemorrhage.Methods 80patients with cerebral hemorrhage in our hospital from 2007to 2010were selected and taken as the observation group.Meanwhile,64healthy cases similar with patients in age and gender were considered as the control group.Enzyme-linked immunosorbent assay(ELISA)was applied to test the ACA level of patients with cerebral hemorrhage in the onset of one day and two weeks,and CT was used to detect the hematoma volume and analyze the relationship between the level of ACA and the condition of patients with cerebral hemorrhage.Results The positive rate of ACA in the observation group(36.25%)was higher than that of control group(9.38%).The observation group was further divided into the hematoma enlargement group and hematoma invariant group.The positive rate of ACA in the hematoma enlargement group(65.52%)was higher than that in hematoma invariant group(19.61%).The positive rate of ACA of observation group in the onset of one day was higher than that of observation group in the onset of two weeks.Conclusion The positive rate of ACA has an important effect to diagnose cerebral hemorrhage for patients.

关 键 词：ACA 脑出血 

分 类 号：R743.34[医药卫生—神经病学与精神病学]