Fe_3O_4微粒碘油平阳霉素乳剂介入栓塞治疗海绵状肝血管瘤的疗效观察  

Treatment efficacy of hepatic cavernous hemangioma by transcatheter arterial Fe_3O_4 microparticle iodipin pingyangmycin emulsion embolization

作　　者：孙锋[1] 杨青[2] 王家平[2] 童玉云[2] 李迎春[2] 朱洪[1] 

机构地区：[1]昆明医学院第二附属医院肝胆外科,昆明650101 [2]昆明医学院第二附属医院放射科,昆明650101

出　　处：《消化肿瘤杂志（电子版）》2009年第2期114-117,共4页Journal of Digestive Oncology(Electronic Version)

摘　　要：目的探讨Fe_3O_4微粒碘油平阳霉素乳剂介入肝动脉栓塞术治疗的海绵状肝血管瘤的疗效。方法随访观察3年来在我院行Fe_3O_4微粒碘油平阳霉素乳剂介入肝动脉栓塞术治疗海绵状肝血管瘤的患者61例,对海绵状肝血管瘤患者介入栓塞术成功率、治疗前后CT复查的瘤体大小的变化、术后并发症、肝功能等进行统计分析。结果本组患者的介入栓塞术成功率为100%,病灶随术后时间的增加呈进行性缩小。本组研究患者(n=61),术前瘤体直径(8.47±2.27)cm,术后3个月时瘤体直径(5.75±1.40)cm,术后6个月时瘤体直径(3.51±0.82)cm,3个时期瘤体直径大小差异均有统计学意义(P<0.05)。治疗对肝功能无影响,除部分患者出现术后低热和肝区疼痛外,无严重并发症。结论 Fe_3O_4微粒碘油平阳霉素乳剂介入栓塞治疗海绵状肝血管瘤是一种安全、有效、微创的治疗方法。Objective To investigate the treatment efficacy of cavernous hemangioma of the liver by transcatheter arterial Fe_3O_4 microparticle iodipin pingyangmycin emulsion embolization. Methods From January 2005 to June 2008,a total of 61 patients with cavernous hemangioma of the liver were enrolled in the study.The success rate of transcatheter arterial embolization,tumor size after treatment,complications and liver function were analyzed.Results The success rate of transcatheter arterial embolization were 100%.Tumor size after treatment decreased progressively with time.The tumor size was(8.47±2.27)cm in diameter before embolization,(5.75±1.40)cm and(3.51±0.82)cm 3 and 6 monthes after the embolization,respectively(P<0.05).There were no effect on liver function and complications except postoperative low-grade fever and hepatalgia.Conclusion Transcatheter arterial Fe_3O_4 microparticle iodipin pingyangmycin emulsion embolization was a safe, effective and microinvasive therapy to cavernous hemangioma of the liver.

关 键 词：Fe3O4微粒碘油平阳霉素乳剂 栓塞治疗 海绵状肝血管瘤 

分 类 号：R735.7[医药卫生—肿瘤]