β_1-adrenergic receptor(Arg389Gly) polymorphism and response to bisoprolol in patients with chronic heart failure  

作　　者：俞文萍 

机构地区：[1]Dept Cardiol Tongji Hosp,Tongji Univ,Shanghai 200065

出　　处：《China Medical Abstracts(Internal Medicine)》2006年第4期193-194,共2页中国医学文摘（内科学分册（英文版）

摘　　要：Objective The purpose of this study was to investigate the relation between the Arg389Gly polymorphism of theβ1-AR gene and chronic heart failure (CHF) and to evaluate the effect of this polymorphism on clinical response toβ-adrenoceptor blockade (bisoprolol) in patients with CHF. Methods One hundred and ten patients with stable CHF receiving basic therapy for heart failure were included. Before initiation and 3 months af-

关 键 词：ADRENERGIC Arg389Gly hundred LVESD LVEDD receiving INITIATION MORPHISM substantially eater 

分 类 号：R541.6[医药卫生—心血管疾病]