Patients with type 1 diabetes mellitus(T1DM)experience multiple episodes of hypoglycemia,resulting in dysfunctional counter-regulatory responses with time.The recent experimental study by Jin et al explored the role o...
the Shenzhen Science and Technology Innovation Committee(grant numbers JCYJ20200109142444449,JCYJ20210324120007021);the National Natural Science Foundation of China(grant numbers 31801196);Basic and Applied Basic Research Foundation of Guangdong Province(grant numbers 2022A1515110645).
Norepinephrine(NA),a stress hormone,can accelerate hair graying by binding toβ2 adrenergic receptors(β_(2)AR)on melanocyte stem cells(McSCs).From this,NA-β_(2)AR axis could be a potential target for preventing the ...
The use of beta(β)-blockers during septic shock aimed at countering peripheral adrenergic stress may be justified by the early reduction in deleterious effects resulting from sympathetic overactivation,and could impr...
When the coronavirus disease 2019(COVID-19)pandemic spread globally from the Hubei region of China in December 2019,the impact on elderly people was particularly unfavorable.The mortality associated with severe acute ...
Background:In this systematic review,we summarize the aetiology as well as the current knowl-edge regarding thermo(dys)regulation and hypothermia after severe burn trauma and aim to present key concepts of pathophysio...
supported by Progetti di Rilevante Interesse Nazionale(PRIN)2017。
The subgranular zone (SGZ) of the hippocampal dentate gyrus is one of the few central nervous system regions where generation of adult born neurons occurs physiologically.This process,referred to as adult hippocampal ...
supported by the grants from the National Natural Science Foundation of China(Nos.31871177 and 31401006);Scientific and Technological Innovation Program of Higher Education Institutions in Shanxi Province(No.201802059);the Graduate Educational Innovation Project of Shanxi Province(No.2018129).
Autophagy reduction has been confirm ed as an im portant mechanism in apoptosis induction.Our previous study showed that decreased autophagy induced by Pi-adrenoceptor autoantibodies(Pi-AAs)enhanced cardiom yocyte apo...
Medical therapy for clinical benign prostatic hyperplasia(BPH)has advanced significantly in the last 2 decades.Many new a1 antagonists and 5a reductase inhibitors(5ARi)are now commercially available.The practicing uro...
supported by the National Natural Science Foundation of China(No.81202602/81373486)
Background Treatment of rats with the beta-adrenergic agonist Isoprenaline(ISO) results in cardiac hypertrophy and myocardial fibrosis.In the present work,we aimed to study the in vivo effects of ISO on serum levels...