Simulation of hemodynamics in portal vein hypertension using CFD  

作　　者：Xiao Li Yansong Pu Peng Nie Zongfang Li Bin Chen 

机构地区：[1]State Key Laboratory of Multiphase Flow in Power Engineering,Xi'an Jiaotong University [2]Second Affiliated Hospital,Xi'an Jiaotong University [3]Department of Radiology,Huaihe Hospital of Henan University

出　　处：《医用生物力学》2013年第S1期99-101,共3页Journal of Medical Biomechanics

基　　金：supported by National Science Foundation of China(51176152);Specialized Research Fund for the Doctoral Program of Higher Education(20120201110070);the Fundamental Research Funds for the Central University(xjj2012115)

摘　　要：Introduction Liver cirrhosis generally occurs with the hemodynamic changes during the portal vein hypertension and finally leads to the atrophy of the right lobe of the liver and hepatic failure^[1].According to the hemodynamic changes,a hypothesis has been proposed that the liver volume is related to the istribution of blood from the splenic vein（SV）that involves nutrition from spleen and pancreas^[2,3].The objective of the present paper is to simulate the blood flow in real models of portal vein hypertension and validate the hypothesis using computational fluid dynamics（CFD）method.Methods This study includes 2 patients with liver cirrhosis and a set of 4 normal subjects.Introduction Liver cirrhosis generally occurs with the hemodynamic changes during the portal vein hypertension and finally leads to the atrophy of the right lobe of the liver and hepatic failure[1].According to the hemodynamic changes,a hypothesis has been proposed that the liver volume is related to the istribution of blood from the splenic vein（SV）that involves nutrition from spleen and pancreas[2,3].The objective of the present paper is to simulate the blood flow in real models of portal vein hypertension and validate the hypothesis using computational fluid dynamics（CFD）method.Methods This study includes 2 patients with liver cirrhosis and a set of 4 normal subjects.Computed

关 键 词：cirrhosis HEMODYNAMIC nutrition PANCREAS SPLENIC ATROPHY hypothesis validate finally SPLEEN 

分 类 号：R318.01[医药卫生—生物医学工程]