New Design of Textile Vascular Prostheses for the Reconstruction of Small Diameter Vascular Blood Vessels  

作　　者：CHRZANOWSKA Olga STRUSZCZYK Marcin Henryk KRUCINSKA Izabella 

机构地区：[1]Department of Material and Commodity Sciences and Textile Metrology,Center of Advanced Technologies of Human Friendly Textiles PRO HUMANO TEX,Faculty of Material Technologies and Textile Design,University of Technology

出　　处：《Journal of Donghua University(English Edition)》2013年第5期401-405,共5页东华大学学报（英文版）

基　　金：European Regional Development Fund(No.WND-POIG.01.03.01-00-007/08-00)

摘　　要：The general object of research is to design new idea of the semi-biodegradable,multilayered vascular prosthesis used for the reconstruction of significantly small diameter vascular vessels( microreconstruction). The paper studies the selection of appropriate sterilization technique for resorbable tubular structures made of poly( L-lactide-co-glicolide)( PLAGA) and nonbiodegradable tubular structures made of polypropylene( PP). The designed grafts are characterized by the physical properties as well as mechanical properties according to ISO 7198 ∶ 1998 Standard.Moreover,the process of the grafts fabrication will be explained considering the stages affected the critical properties of the elaborated textile implants. The increase of PLAGA melt-electrospun tubular structures mechanical properties was observed due to the thermal stabilization use. The ethylene oxide( EO) and steam sterilization had a destructive effect on the designed PLAGA meltelectrospun tubular, fibrous structures, whereas the irradiation yielded in the changes in mechanical and physical properties on the acceptable level,taking into account the future clinical applications.The general object of research is to design new idea of the semi-biodegradable,multilayered vascular prosthesis used for the reconstruction of significantly small diameter vascular vessels( microreconstruction). The paper studies the selection of appropriate sterilization technique for resorbable tubular structures made of poly( L-lactide-co-glicolide)( PLAGA) and nonbiodegradable tubular structures made of polypropylene( PP). The designed grafts are characterized by the physical properties as well as mechanical properties according to ISO 7198 ∶ 1998 Standard.Moreover,the process of the grafts fabrication will be explained considering the stages affected the critical properties of the elaborated textile implants. The increase of PLAGA melt-electrospun tubular structures mechanical properties was observed due to the thermal stabilization use. The ethylene oxide( EO) and steam sterilization had a destructive effect on the designed PLAGA meltelectrospun tubular, fibrous structures, whereas the irradiation yielded in the changes in mechanical and physical properties on the acceptable level,taking into account the future clinical applications.

关 键 词：VASCULAR PROSTHESES melt-electrospinning MELT-BLOWN STERILIZATION 

分 类 号：TS106.67[轻工技术与工程—纺织工程]