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Rapamycin as a preventive intervention for Alzheimer’s disease in APOE4 carriers:Targeting brain metabolic and vascular restoration: 《Neural Regeneration Research》2026年第2期685-686,共2页Ai-Ling Lin Chetan Aware; supported by National Institute on Aging(NIH-NIA)R01AG054459(to ALL).; Alzheimer’s disease(AD)is the most common form of dementia,affecting over 50 million people worldwide.This figure is projected to nearly double every 20 years,reaching 82 million by 2030 and 152 million by 2050(Alzhe...; 关键词：lipid transporterexists Dementia alzheimer s disease ad RAPAMYCIN Brain metabolic Vascular restoration Amyloid beta plaques APOE

Generation of brain vascular heterogeneity:recent advances from the perspective of angiogenesis: 《Neural Regeneration Research》2025年第7期2013-2014,共2页Nathanael J.Lee Ryota L.Matsuoka; supported by funding from the National Institutes of Health(R01 NS117510)(to RLM)。; Heterogeneous proper t i es of vascular endothelial cells in the brain:The brain displays large energy dynamics and consumption,and this high level of metabolic demands is fulfilled by a continuous supply of glucose a...; 关键词：ANGIOGENESIS HOMEOSTASIS network

EGFR-mediated crosstalk between vascularendothelial cells and hepatocytes promotesPiezo1-dependent liver regeneration: 《Genes & Diseases》2025年第3期411-427,共17页Yuelei Hu Guifang Du Chao Li Rui Wang Juan Liu Yunfang Wang Jiahong Dong; supported by the National Key Research and Development Program of China(No.2022YFA1103400);the CAMS Innovation Fund for Medical Sciences(No.2019-I2M-5e056);the National Natural Science Foundation of China(No.81930119,92168207,32371477,82090051);the Precision Medicine Research Program of Tsinghua University(No.10001020612);the National High Level Hospital Clinical Research Funding(China)(No.2022-NHLHCRF-LX-03-0102).; Hepatocyte proliferation is essential for recovering liver function after injury. Inliver surgery, the mechanical stimulation induced by hemodynamic changes triggers vascularendothelial cells (VECs) to secrete large a...; 关键词：EGFR Hemodynamic changes Liver regeneration Piezo1 Vascular endothelial cells

Reduced choroidal vascular index and choroid structural changes extended beyond subfoveal area in chronic central serous chorioretinopathy eyes with macular neovascularization: 《International Journal of Ophthalmology(English edition)》2025年第5期853-859,共7页Xiang-Gui Zhang Zhen-De Deng Yan-Nian Hui Zhen Huang Ya Ye Ming Yan Yan-Ping Song; Supported by General Program of National Natural Science Foundation of China(No.82471110);National Key Research and Development Program of China(No.2022YFC2502805);Postdoctoral Foundation of General Hospital of Central Theater Command(No.20210517KY04).; AIM:To investigate the choroidal vascular index(CVI)and the choroidal structural changes beyond the subfoveal area(analyzed across a 20 mm×24 mm scanning area)in eyes with chronic central serous chorioretinopathy(cCS...; 关键词：central serous chorioretinopathy macular neovascularization choroidal vascular index choroidal thickness optical coherence tomography angiography

Management of perifoveal exudative vascular anomalous complex with laser treatment: a case report: 《International Journal of Ophthalmology(English edition)》2025年第5期965-968,共4页Qing Chen Bin-Jian Wang Yu-Zhu Gao Xue Wu Ming Zhang; Supported by the 1.3.5 Project of West China Hospital of Sichuan University(No.2023HXFH043);Sichuan Natural Science Foundation(No.24NSFSC1718).; Dear Editor,We describe a case diagnosed with exudative perifoveal vascular anomalous complex(ePVAC)successfully treated with focal laser photocoagulation(577 nm),achieving a favorable prognosis with best-corrected vi...; 关键词：cystic macular edema me focal laser photocoagulation best corrected visual acuity laser treatment macular edema early onset non epvac exudative perifoveal vascular anomalous complex epvac successfully perifoveal exudative vascular anomalous complex

Central vascular ligation and complete mesocolon excision vs D3 lymphadenectomy: Standardization of surgical technique: 《World Journal of Gastrointestinal Surgery》2025年第4期435-439,共5页Sung Uk Bae; Surgical advancements have transformed colorectal cancer treatment, withcomplete mesocolic excision (CME) becoming a crucial method to guaranteeoncological safety and effectiveness. The article by Yadav emphasized the...; 关键词：LAPAROSCOPY MESOCOLON Colonic neoplasm Lymph node Surgical technique

Promising four-dimensional flow magnetic resonance imaging technique for vascular flow analysis in children: 《World Journal of Radiology》2025年第4期47-49,共3页Jian-She Yang; Leesmidt et al present a comprehensive analysis of abdominal vascular flow in children using four-dimensional(4D)flow magnetic resonance imaging(MRI),aim to establish normal hemodynamic values for the abdominal viscer...; 关键词：Four-dimensional flow magnetic resonance imaging Hemodynamic values Imaging DIAGNOSIS Vascular flow

The endovascular treatment strategies of cerebrovascular injuries in traumatic brain injury: 《Chinese Journal of Traumatology》2025年第2期81-90,共10页Shuo Leng Wentao Li Yu Cai Yi Zhang; supported by the Jiangsu Province Science and Technology Support Project(No.:BE2023769)。; Vasculature injury occurs rarely in traumatic brain injury but increases lifetime risk of ischemic or hemorrhage stroke.The diverse and nonspecific clinical manifestations make the diagnosis and treatment of these inj...; 关键词：Endovascular treatment Traumatic cerebrovascular injury STROKE Vascular lesions

Vascular Ossification in the Developing Brain:A Case Study of Pediatric Sturge Weber Syndrome: 《Neuroscience Bulletin》2025年第3期520-524,共5页Ranxi Chen Shuhui Xie Jin Gao Shuli Zhang Xiaobin Zhang Yi Yao Gengxiu Zheng Fengpeng Wang Zili Liu Xuefeng Shen; supported by the Natural Science Foundation of Guangdong Province(2022A1515010297);the National Natural Science Foundation of China(32100765);the Xiamen Medical Health Science and Technology Project(3502Z20194098);the Shenzhen-Hong Kong-Macao Science and Technology Innovation Project(SGDX2020110309280100).; Dear Editor,Sturge-Weber Syndrome(SWS)is a rare congenital neurocutaneous syndrome[1,2],with an estimated prevalence of 0.19 in 100,000 annually[3].It is a non-hereditary disease linked to a somatic mutation in the GN...; 关键词：vascular calcification vascular malformations brain calcification bc brain calcification congenital neurocutaneous syndrome somatic mutation vascular ossification Sturge Weber syndrome

High-performance laser speckle contrast image vascular segmentation without delicate pseudo-label reliance: 《Journal of Innovative Optical Health Sciences》2025年第1期117-133,共17页Shenglan Yao Huiling Wu Suzhong Fu Shuting Ling Kun Wang Hongqin Yang Yaqin He Xiaolan Ma Xiaofeng Ye Xiaofei Wen Qingliang Zhao; supported by grants fromthe State Key Laboratory of Vaccines for Infectious Diseases,Xiang An Biomedicine Laboratory(2023XAKJ0101031);National Natural Science Foundation of China(81971665);Natural Science Foundation of Fujian Province(2021J011366);Medical and Health Guidance Project of Xiamen(3502Z20214ZD1016);Xiamen Health High-Level Talent Training Program,Ningxia Hui Autonomous Region Key Research and Development Program(2022BEG03127);Fundamental Research Funds for the Central Universities of China(20720210117);Fujian Province Science and Technology Plan Guiding Project(2022Y0002);National Natural Science Foundation of China(62005048);Natural Science Foundation of Fujian Province(2020J01158);Ministry of Education Industry-university Cooperative Education Project(220606053295218);XMU Undergraduate Innovation and Entrepreneurship Training Programs(2023X805,2023X808,2023Y1109).; Laser speckle contrast imaging(LSCI)is a noninvasive,label-free technique that allows real-time investigation of the microcirculation situation of biological tissue.High-quality microvascular segmentation is critical ...; 关键词：Biomedical imaging laser speckle contrast imaging vessel segmentation weakly supervised learning MICROCIRCULATION

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