胸段食管癌转移淋巴结数量与生存率关系的研究  

Study on survival analysis of lymph node metastasis in carcinoma of thoracic esophageal cancer

作　　者：王春利[1] 张双平[1] 冯守山[1] 韩斐[1] 马炎炎[1] 郭伟[1] 童国平[1] 游志恒[1] 郭棕亮[1] 王晓军[1] 

机构地区：[1]不详

出　　处：《肿瘤研究与临床》2008年第10期679-681,共3页Cancer Research and Clinic

摘　　要：目的 探讨胸段食管癌转移淋巴结数最与食管癌预后的关系.方法 分析1995年7月至2005年7月在山西省肿瘤医院行胸段食管癌根治术的患者1140例的临床资料,并进行生存情况分析.结果 淋巴结转移数量与食管癌的生存率呈负相关(P=0.000);患者淋巴结切除数量≥8枚、<8枚时,淋巴结转移度差异有统计学意义(P=0.000).结论 食管癌淋巴结转移数量与患者预后呈显著相关性,能反映其预后,建议pTNM分期将淋巴结转移数考虑在N1内.Objective To study the effect of positive lymph node number on the survival of patients with esophageal carcinoma. Methods From July 1995 to July 2005, a total of 11,447 resected lymph nodes were obtained from 1140 patients who underwent curative resection of the primary tumor with systematic lymphadenectomy at Shanxi cancer hospital. The survivals were analysed by life tables and Kaplan-Meier methods, the related factors of lymph node metastasis were assessed by Chi-square test. Results The number of positive lymph nodes was negatively related to survival rates of esophageal carcinoma. According to the number of lymph nodes resected (≥8 nodes versus <8 nodes), there was significant difference in metastatic lymph node ratio. Conclusion The number of positive lymph node can reflect the prognosis of patients better. The authors suggest that the modification of the tumor-lymphnode-metastasis (TNM) staging classification (TNM) to include the number of positive lymph nodes in the N1 category.

关 键 词：食管肿瘤 外科手术 淋巴转移 预后 存活率分析 

分 类 号：R735[医药卫生—肿瘤]