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作 者:唐劭年[1] 胡宗继[1] 巴特尔[1] 李哲[1] 刘立雄[1]
机构地区:[1]中山大学附属东华医院神经内科,广东东莞523110
出 处:《中国医药科学》2014年第9期205-207,共3页China Medicine And Pharmacy
摘 要:目的为了进一步探讨中老年大面积脑梗死疾病的非手术治疗效果,探讨脑梗死伤残率与脑梗死后抑郁症之间的关系。方法根据我院2007年8月~2013年8月间收治的中老年大面积脑梗死疾病患者的临床资料,选取75例伴脑梗死后抑郁症患者,采用抗脑梗死药物以及抗抑郁药物进行治疗,观察患者治疗情况以及脑梗死与脑梗死后抑郁症的相对关系。结果中年患者35例,死亡率为31.43%,残障率为22.86%,患者远期预后较老年组好;老年患者40例,死亡率为37.5%,残障率为30%,患者早期以及伴合并症者死亡率较高,预后差。脑梗死后抑郁症治疗情况:重度患者疗效差,内源性患者疗效差,中轻度患者疗效较佳。脑梗死与脑梗死后抑郁相互作用。结论中老年大面积脑梗死患者采用保守药物治疗效果较为稳定,但存在一定的局限性,与手术治疗相比治疗过程更安全,对患者机体环境要求较低,可做特殊患者以及不适做手术的脑梗死患者一般治疗方式,控制患者抑郁症情况也可降低死亡以及残障率。Objective To further explore the non-surgical curative effect of massive cerebral infarction for middle-aged and elderly patients, and to analyze the relations between the disability rate of cerebral infarction and cerebral infarction-induced depression. Methods According to the clinical data obtained from middle-aged and elderly patients with massive cerebral infarction who were admitted to our hospital from August 2007 to August 2013,75 patients with cerebral infarction-induced depression were selected and given anti-cerebral infarction drugs and anti-depression drugs for the treatment.The curative effect and the relations between cerebral infarction and depression were observed. Results There were 35 middle-aged patients.Their mortality rate was 31.43%,disability rate was 22.86% and long-term prognosis was better than that of the elderly patients;there were 40 elderly patients. Their mortality rate was 37.5% and the disability rate was 30%. The mortality rate was higher for early stage and complications,and the prognosis was poor. Conclusion Of treating cerebral infarction-induced depression:the curative effect was poor for severe patients and endogenous patients, and better for mild and moderate patients. The cerebral infarction was interacting with cerebral infarction-induced depression. Conclusion The curative effect of conservative medicine is stable for treating massive cerebral infarction for middle-aged and elderly patients,but has certain limitations.Its treatment process is safer than that of a surgical treatment, and it has a lower requirement for patients''health condition.The method can be used as a general treatment for special patients or patients not suitable for surgery.Controlling patients''depression also helps lower mortality and disability rate.
分 类 号:R743.33[医药卫生—神经病学与精神病学]
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