ADC值诊断结节或弥漫生长外周带前列腺癌的价值初步评价  

A preliminary evaluation of diagnostic performances of ADC value on nodular and diffusely growing prostate cancers in peripheral zone

作　　者：陈穗惠[1] 韩邵军[1] 刘新球[1] 李雪[1] 唐艳华[2] 李璐[2] 安宁豫[1] 

机构地区：[1]中国人民解放军总医院放射科,北京100853 [2]中国人民解放军放射科

出　　处：《微创泌尿外科杂志》2014年第6期338-342,共5页Journal of Minimally Invasive Urology

摘　　要：目的:对ADC值诊断结节状及弥漫生长外周带前列腺癌的价值进行初步评价。方法:对病理证实的35例外周带前列腺癌及22例外周带非肿瘤性病变的最小ADC值进行回顾性分析。结果:诊断结节状外周带前列腺癌,两位评估者所获的ROC曲线下面积(AUCs)分别为0.713(95%CI:0.566~0.866)及0.748(95%CI:0.605~0.890),诊断弥漫生长的外周带前列癌,评估者1及2的AUCs分别为0.943(95%CI:0.854,1.033)及0.876(95%CI:0.729,1.023),当ADC截断值设为1.02×10-3 mm2/s时,两种形状外周带前列腺癌的诊断的正确率分别为67.4%~70.5%及84.0%~85.7%。结论:ADC值对于外周带弥漫生长前列腺癌的诊断价值较高,对于外周带结节状前列腺癌的诊断价值中等。Objective:To retrospectively assess the diagnostic performances of ADC value on nodular and diffusely growing prostate cancers for prostate cancers in peripheral zones.Methods:Two readers retrospectively evaluated the ADC values of 35 cases of pathologically proven prostate cancer and 22 cases of pathologically proven non-cancerous diseases in peripheral zones.Results:For reader 1and reader 2,the AUCs for nodular prostate cancer diagnoses in peripheral zones were 0.713(95% CI:0.566,0.866)and 0.748(95% CI:0.605,0.890)respectively,and 0.943(95% CI:0.854,1.033)and 0.876(95% CI:0.729,1.023)for diffusely growing prostate cancer diagnoses in peripheral zones.When cut-off value of ADC was set to 1.02×10-3 mm2/s,the diagnostic accuracies of ADC value on these two shapes of prostate cancers in peripheral zone were 67.4%to 70.5%and 84.0%to-85.7%respectively.Conclusions:The diagnostic performances of ADC was relative good on diffusely growing prostate cancers and mean on nodular prostate cancer in peripheral zones.

关 键 词：前列腺癌 边缘区 磁共振成像 扩散加权成像 表观扩散系数 

分 类 号：R737.25[医药卫生—肿瘤]