治疗支原体感染药物敏感性7年前后比较  

Comparative Study of Drug Sensitivity to Mycoplasma Infection Between 7 Years Ago and 7 Years Later

作　　者：杨文林[1] 杨健[1] 叶婷[1] 黄新宇[1] 张红娟[1] 陈思华[1] 

机构地区：[1]广州医学院附属第二医院皮肤科,广州市510260

出　　处：《中国医院用药评价与分析》2004年第3期168-169,共2页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的 :分析了解 1996年以来非淋菌性尿道炎 (NGU)患者泌尿生殖道支原体感染和对不同药物体外敏感性的变化。方法 :采用MycoplasmaIST试剂盒检测NGU患者泌尿生殖道支原体及药物敏感性 ,试验结果与 7年前的数据进行比较。结果 :与1996年相比 ,解脲支原体 (Uu)阳性率及合并衣原体感染情况与 7年前相近 ,但人型支原体 (Mh)阳性率下降 ;支原体对红霉素、多西环素的耐药率下降 ,对喹诺酮类药物仍有较高的耐药率 ,对交沙霉素、原始霉素的耐药率仍很低。结论 :近年解脲支原体感染率无明显增加 ,人型支原体感染有所减少 ,支原体的耐药性发生了变化 ,应作定期监测。交沙霉素仍可作为治疗非淋菌性尿道炎的有效药物。OBJECTIVE: To study mycoplasma infection of genitourinary tract in patients with nongonococcal urethritis(NGU) and the changes of the sensitivity to different kinds of drugs since 1996. METHODS: Urethral (or cervical)mycoplasma specimens were taken from the patients with NGU and detected by mycoplasma IST kit. The results were compared with the data of seven years ago. RESULTS: Compared with the year 1996, MU positive rate and complicated choamydiae infection rate were similar to that of seven years ago , but human mycoplasma positive rate decreased. The resistance of mycoplasma to antimicrobial such as erythromycin and doxycyclin was low, to quinolines was still high and to josamycin and pristinamycin was still low.CONCLUSION: The positive rate of MU infection has no significant increase in recent years. But positive rate of human mycoplasma infection has obviously reduced. The resistance of mycoplasma has changed, so it should be monitored regularly. Josamycin is still the efficient drug for the treatment of NGU.

关 键 词：支原体感染 药物敏感性 非淋菌性尿道炎 MPC 性传播疾病 

分 类 号：R691.3[医药卫生—泌尿科学] R978.1[医药卫生—外科学]