气相色谱-质谱联用技术分析中毒样品中四种生物碱  

Determination of 4 alkaloids in poisoning samples by gas chromatography/mass spectrometry

作　　者：杨玉林[1] 温忆敏[1] 芮振荣[1] 沈朝烨[1] 

机构地区：[1]上海市疾病预防控制中心,上海200336

出　　处：《中国卫生检验杂志》2004年第3期272-273,共2页Chinese Journal of Health Laboratory Technology

摘　　要：本文利用气相色谱 质谱 (GC MS)联用技术定性分析了中毒样品中四种生物碱 -莨菪碱、钩吻碱、士的宁、马钱子碱。采取调节溶液pH至 8～ 9,用氯仿进行液 -液提取 ,用气相色谱 质谱检测器进行分析。四种生物碱的最低进样量为 1.3～ 5 0ng。结果表明 ,该方法可用于中毒样品中生物碱的快速分析。After pH value was adjusted to 8～9,4 alkaloids including hyoscyamine,gelsemine,strychnine and brucine in poisoning samples were determined by gas chromatography/mass spectrometry (GC/MS).The detection limit was 1.3～50ng.The results show that the method is simple,rapid and accurate.

关 键 词：气相色谱-质谱联用技术 中毒样品 生物碱 莨菪碱 钩吻碱 

分 类 号：O657.71[理学—分析化学] R155.32[理学—化学]