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机构地区:[1]北京大学天然药物及仿生药物国家重点实验室,北京100083
出 处:《Journal of Chinese Pharmaceutical Sciences》2004年第2期87-91,共5页中国药学(英文版)
基 金:NationalNaturalScienceFoundationofChina( 2 9972 0 0 4)
摘 要:Aim To study the saponin constituents of the seeds of Aesculus chinensis Bunge var. chekiangensis (Hu et Fang) Fang. Methods Compounds were separated and purified by macroreticular resin column chromatography and high-performance liquid chromatography. Their structures were elucidated by spectroscopic and hydrolysis analysis. Results Six compounds were isolated from the 70% ethanolic extracts. They were identified as escins IVc, IVd, Ia, Ib, isoescins Ia and Ib, respectively. Conclusion The above compounds were obtained from the seeds of Aesculus chinensis Bunge var.chekiangensis (Hu et Fang) Fang for the first time.目的 研究传统中药浙江七叶树AesculuschinensisBungevar.chekiangensis (HuetFang)Fang种子中的皂苷类成分。方法 采用大孔树脂柱色谱、高效液相色谱等方法进行分离和纯化 ,根据化合物的谱学数据鉴定其结构。结果 从浙江七叶树种子的 70 %乙醇提取物中分得 6个化合物 ,分别鉴定为七叶树皂苷 (escins)IVc、IVd、Ia、Ib和异七叶树皂苷 (isoescins)Ia、Ib。结论 这
关 键 词:Aesculus chinensis Bunge var. chekiangensis TRITERPENOIDS ESCIN isoescin
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