超声检测脑血管病高危人群颈动脉内皮舒张功能  

Clinic Value of Non-Invasive Ultrasonic Test of Endothelia Dependent Diastolic Function of Carotid Artery on People with High Risk of Cerebralvasculr Diseases

作　　者：贺顺龙[1] 朱兆洪[1] 陈宝国[1] 林煜[1] 白建萍[1] 邓国良[1] 梁玉玲[1] 

机构地区：[1]中国人民解放军第421医院神经内科,广东省广州市510318

出　　处：《中国动脉硬化杂志》2004年第2期206-208,共3页Chinese Journal of Arteriosclerosis

摘　　要：探讨一种简便易行、可靠实用的无创性颈动脉检测方法 ,为脑卒中的早期防治提供依据。应用高分辨超声分别对 5 3例脑血管病高危人群和 5 3例健康成年人在休息时、反应性充血时和含服硝酸甘油后的颈内动脉内径变化进行测定 ,数据取连续检测 3次平均值。结果发现 ,超声声像图显示高危组患者颈动脉内膜均有不同程度增厚 ,管腔狭窄 ;在反应性充血试验和含服硝酸甘油后 ,健康组颈动脉明显扩张 ,与基础值比较有显著性差异 ,而高危组颈动脉虽有扩张 ,但与基础值比较无显著性差异。结果提示 ,健康人的颈内动脉内皮依赖性舒张具有明显的可调节性 ,血流增加可引起内皮依赖性舒张 ;而高危组虽随血流增加可使内皮依赖性舒张 ,但调节能力明显下降 ,同时表明本测定方法简便而可行。Aim To probe a simple, convenient, non-invasive and credible method to measure people's carotid artery, and to provide an early way to prevent and cure stroke. Methods High differentiate ultrasonic system was used in our research to measure 53 cases with high risk of stroke and 53 healthy cases. The changes of inner-diameter of carotid artery were measured at relaxation, reactive congest and after taking glonoine. Results The ultrasonic audio image showed that inner membrane incrassated and lumen diminished in high risk of stroke group, in reactive congest test and after taking glonoine, carotid artery dilated notably in healthy group. Conclusion Endothelia dependent diastolic function of carotid artery were adjustive remarkably in healthy people. With the flow of blood stream raised, the endothelia dependent dilatation increased in healthy group; the power of regulating of carotid artery dropped observably in high risk of stroke group. The research also indicated that this measure is simple, convenient and credible.

关 键 词：神经病学 超声检测颈动脉内皮舒张功能 超声检测 脑血管病 颈动脉 内皮舒张功能 

分 类 号：R741[医药卫生—神经病学与精神病学]