病灶切除联合热灼术治疗顽固性继发癫癎的疗效初探  

Treatments of intractable secondary epilepsy by lesionectomy combining with bipolar coagulation.

作　　者：杨忠旭[1] 栾国明[2] 

机构地区：[1]首都医科大学北京天坛医院神经外科北京市神经外科研究所,100050 [2]卫生部北京医院神经外科

出　　处：《中国综合临床》2004年第7期619-620,共2页Clinical Medicine of China

摘　　要：目的　探讨病灶切除联合灶皮质横纤维热灼术治疗顽固性继发癫的效果。方法　对病灶切除联合热灼组与病灶及周围非功能区灶皮质切除组的疗效随访 2 .5～ 5 .5年 ,平均 4 .0年 ,并进行比较。结果　病灶切除联合热灼组效果明显优于病灶及周围非功能区灶皮质切除组 ,两组存在显著性差异(P <0 .0 1)。同时 ,病灶切除加热灼无永久性术后并发症。结论　病灶切除联合皮质灶热灼术是治疗顽固性继发癫安全有效的创新方法 。Objective To explore the clinical effects of lesionectomy combining with bipolar coagulation to the surrounding cortexes(BCSC) with epileptogenic foci on intractable secondary epilepsy. Methods The patients were managed by lesionectomy and resection of the surrounding non-functional cortexes with epileptogenic foci and lesionectomy combining with BCSC who were followed up for 2.5-5.5 years, on an average of 4 years. Results The effect of BCSC group was significantly superior to that of lesionectomy group(P<0.01). Meanwhile the BCSC group had no permanent post-operative complication. Conclusion Lesionectomy combining with BCSC is an innovative, effective and safe management for treating intractable secondary epilepsy, but the long-term efficacy needs further study.

关 键 词：癫痫 热灼术 脑外科手术 

分 类 号：R742.1[医药卫生—神经病学与精神病学]