食管癌患者血清SIL-2R和TNF-α水平测定的临床意义  

Clinical significance of serum SIL-2R and TNF-α levels in patients with carcinoma of esophagus

作　　者：齐华国[1] 

机构地区：[1]江苏省灌云县人民医院检验科,222200

出　　处：《淮海医药》2004年第5期359-360,共2页Journal of Huaihai Medicine

摘　　要：目的　探讨了可溶性白细胞介素 - 2受体 (SIL- 2 R)和肿瘤坏死因子 (TNF- α)水平与食管癌的关系及临床意义。方法　分别应用 EL ISA法及 RIA法测定 38例食管癌患者血清中 SIL - 2 R和 TNF-α水平 ,并与 35名正常健康人作比较。结果　食管癌患者血清 SIL- 2 R水平非常显著地高于正常人组 (P<0 .0 1 )而 TNF- α水平则于正常人组比较差异无显著性 (P>0 .0 5 )。结论　测定 SIL- 2Objective To study the serum levels of soluble interleukin 2 receptor(SIL 2R) and tumor necrosis factor α(TNF α) in patients with carcinoma of esophagus.Methods Serum SIL 2R and TNF α levels were measured in 38 patients with carcinoma of esophagus.SIL 2R was determined with ELISA and TNF α was measured with RIA.Results Serum SIL 2R levels of carcinoma of esophagus group were significantly higher than those of normal controls while levels of TNF α showed no notable difference between two groups.Conclusion The serum SIL 2R concentration can reflect immune status of patients with carcinoma of esophagus.It has an important clinical value.

关 键 词：食管癌 血清 SIL-2R TNF-Α 测定 可溶性白细胞介素-2受体 肿瘤坏死因子 

分 类 号：R735.1[医药卫生—肿瘤] R730.43[医药卫生—临床医学]