One-pot Synthesis of Isoxazolines Using Soluble Polymer-supported Acrylate  

作　　者：商永嘉 王彦广 

机构地区：[1]Department of Chemistry, Zhejiang University

出　　处：《Chinese Journal of Chemistry》2003年第1期7-8,共2页中国化学（英文版）

基　　金：ProjectsupportedbytheNationalNaturalScienceFoundationofChina (No .2 9972 0 37)

摘　　要：An efficient liquid-phase synthesis of isoxazolines through a 1,3-dipolar cycloaddition is described. Soluble polymer-supported acrylate reacted with nitrile oxides generated in-situ, followed by cleavage from the support giving corresponding isoxazolines in high yields and excellent purities.An efficient liquid-phase synthesis of isoxazolines through a 1,3-dipolar cycloaddition is described. Soluble polymer-supported acrylate reacted with nitrile oxides generated in-situ, followed by cleavage from the support giving corresponding isoxazolines in high yields and excellent purities.

关 键 词：poly(ethylene glycol) (PEG) ISOXAZOLINE CYCLOADDITION LIQUID-PHASE 

分 类 号：TQ325[化学工程—合成树脂塑料工业]