supported by the Fund of National Research Centre,Egypt.
Alibrary of novel spiro[pyrazole-4,5′-isoxazoline]-5-one derivatives were designed and synthesized using a concise and efficient one-pot reaction protocol through 1,3-dipolar cycloaddition between 4-benzylidene-3-met...
the financial support for this investigation from the National Natural Science Foundation of China(Nos.21772151,22072111);the Fundamental Research Funds for Central Universities(No.WUT:2021IVA121).
The first example of stereoconvergent 1,3-dipolar cycloaddition of nitrile oxides and nitrile imines with E/Z isomeric mixture of electron-deficient olefins is reported,delivering isoxazolines and pyrazolines bearing ...
With the introduction of various heterocyclic rings at the benzene part of anthranilic diamides, a series of N-pylidylpyrazolecarboxamide derivatives containing isoxazole, isoxazoline and 1,3,4-thiadiazole rings was d...
Supports from the National Natural Science Foundation of China (Nos. 21272257, 21274041 and 21474028)
NTrifluoromethyl and cyclopropyl substituted 2-isoxazolines were synthesized via a DBU-promoted domino reaction of β-trifluoromethyl-/β-cyclopropyl-substituted enones with hydroxylamine. The domino reaction consists...
An expeditious and effective method for synthesis of isoxazoline from aldoximes and activated alkenes using cetyltrimethylammonium cerium nitrate at room temperature is described.Reaction was completed within short ti...
We are grateful to the National Natural Science Foundation of China(20332060);the CAS Academician Foundation of Zhejiang Province.
A mild deselenenylation reaction protocol for the preparation of 3, 5-disubstituted isoxazolines and their further application to 3-methyl-5-substituted isoxazoles both in solution phase and solid phase was reported.
ProjectsupportedbytheNationalNaturalScienceFoundationofChina (No .2 9972 0 37)
An efficient liquid-phase synthesis of isoxazolines through a 1,3-dipolar cycloaddition is described. Soluble polymer-supported acrylate reacted with nitrile oxides generated in-situ, followed by cleavage from the sup...
NNSFC (20074017,29844001) and Visiting Scholar Foundation of Key Lab. In University
The solid-phase synthesis of isoxazolines on 2-polystyrylsulfonamidoethanol resin is reported. 2-Polystyrylsulfonamidoethanol resin 1 was reacted with acryloyl chloride to afford 2-polystyrylsulfonylamidoethyl acrylat...
Asymmetric 1,3-dipolar cycloaddition of nitrite oxides to an acryloyl ester (1) derived from 1, 2:5, 6-di-O-isopropylidene glucose (6) was studied. Solvent and temperature effect was discussed. The single diastereoiso...
Project (No. 95QA14028) supported by the Star of Science;Technology Foundation of Shanghai.
Pinanyldioxy styrylboronic ester (1) was employed for asymmetric 1,3-dipolar cycloaddition with nitrile oxides, optically active Δ2-isoxazolines (3) or 4-hydroxy- Δ2-isoxazolines (4) were obtained. The effect of dif...