早期乳腺癌的保乳综合治疗疗效分析  

Treatment of early stage breast cancer with breast conserving therapy

作　　者：姚青[1] 张聚良[1] 王岭[1] 凌瑞[1] 袁时芳[1] 陈江浩[1] 允军[1] 杨华[1] 

机构地区：[1]第四军医大学西京医院血管内分泌外科,西安710032

出　　处：《临床外科杂志》2004年第2期85-86,共2页Journal of Clinical Surgery

摘　　要：目的　评价早期乳腺癌保乳综合治疗的疗效。方法　保乳组 92例 ,行保留乳房的肿瘤切除加腋窝淋巴结清扫术 ;对照组 60例 ,行乳癌改良根治术。术后给予放疗、全身化疗和 /或内分泌治疗。结果　平均随访 5 7个月 ,保乳组中无局部复发病例 ,3年生存率为 97.2 % ,5年生存率为 89.3 % ,远隔脏器转移率为 6.5 % ;对照组局部复发 2例 ,3年生存率为 97.5 % ,5年生存率为90 .1% ,远隔脏器转移率为 5 .0 % ,两组各指标对比无明显差异 (P >0 .0 5 )。结论　早期乳腺癌采用保乳综合疗法 ,可以达到与根治术相似的治疗效果 。Objective To study the feasibility of breast conserving therapy (BCT) for early stage breast cancer.Methods 92 cases of early stage breast cancer underwent breast-conserving surgery while 60 cases,as a control,underwent modified radical mastectomy,followed by radiotherapy,chemotherapy and/or TAM therapy.Results All cases were followed up for an average of 57 months.In BCT group,no patient had local recurrence.The 3-,5- years survival rate and distant metastasis rate was 97.2%,89.3% and 6.5%,respectively.In the control group, 2 patients had local recurrence. The 3-,5- years survival rate and distant metastasis rate was 97.5%,90.1% and 5.0%,respectively.There was no difference between the two groups (P>0.05).Conclusion BCT for early stage breast cancer may achieve similar results as traditional mastectomy and may be considered as a primary treatment option.

关 键 词：乳腺癌 保乳治疗 改良根治术 

分 类 号：R737.9[医药卫生—肿瘤]