慢性胃炎患者幽门螺杆菌感染与血清胃泌素的关系  

Investigation of relationship between helicobacter pylori infection and serum gastrin in chronic gastritis

作　　者：罗雄[1] 夏于新[2] 王志凤[1] 

机构地区：[1]新疆医科大学第一附属医院消化科,新疆乌鲁木齐830054 [2]兰州军区乌鲁木齐总医院内科,新疆乌鲁木齐830000

出　　处：《新疆医科大学学报》2004年第3期242-243,共2页Journal of Xinjiang Medical University

摘　　要：目的:了解慢性胃炎患者幽门螺杆菌感染与血清胃泌素的关系。方法 :选择本院胃镜下诊断的慢性胃炎患者 5 4例 ,采用放免法测定血清胃泌素浓度 ,用快速尿素酶试验和 Giemsa染色检查是否存在幽门螺杆菌感染。结果 :幽门螺杆菌感染阳性患者血清胃泌素水平明显高于未感染者。 结论:幽门螺杆菌引起血清胃泌素增高 ,进而造成胃酸分泌增多 ,可能是幽门螺杆菌感染致病机制之一。Objective: To investigate the relationship between helicobacter pylori infection and serum gastrin (GAS) in chronic gastritis. Methods: We detected serum GAS by RIA, and HP infection by rapid urease test(RUT) and Giemsa stainning in 54 endoscopy patients. Results: The serum GAS level [(84.51±59.53) pg/ml] in HP positive patients was higher than that [(12.06 ±8.09)pg/ml] in HP negative (P<0.001). Conclution: High gastrin caused by HP infection leading to more gastric acid may be one of the pathogeneses of HP infection.

关 键 词：幽门螺杆菌 胃泌素 慢性胃炎 

分 类 号：R573.3[医药卫生—消化系统] R446.6[医药卫生—内科学]