Community-based Survey of Prevalence and Risk Factors of Syphilis among Injection Drug Users in Sichuan Province, China  

以社区为基础的静脉吸毒人群梅毒感染情况及危险因素研究(英文)

作　　者：阮玉华[1] 何益新[1] 周枫[1] 刘石柱[1] 秦光明[2] 孙乔[2] 刘刚[2] 陈康林 陈显煌 郝沁宁 洪坤学[1] 陈建平[1] 刑辉[1] 邵一鸣 

机构地区：[1]中国疾病预防控制中心性病艾滋病预防控制中心病毒及免疫研究室,北京100050 [2]四川省疾病预防控制中心 [3]西昌市性病麻风病控制中心

出　　处：《Chinese Journal of Sexually Transmitted Infections》2004年第1期1-6,62,共7页中华性传播感染杂志（英文版）

基　　金：Supported by The National Tenth-Five-Year Scientific Championship Project (No. 2001BA705B02) and National Natural Science Foundation of China Project (No. 30170823).

摘　　要：Objectives: To investigate prevalence and risk fac-tors of syphilis infection among injection drug users(IDUs) in Lianshan Yizu Autonomous Region ofSichuan province, China.Methods: From November 8th 2002 to November29th 2002, a community-based cross-sectional surveywas conducted to investigate the demographic charac-teristics and sexual behaviors of a population of IDUs.Blood samples were collected to test for syphilisinfection. A total of 379 subjects were recruitedfor the study through community outreach and peerrecruiting methods.Results: Of 379 IDUs, the syphilis prevalence amongIDUs was 15.3% (58/379). Gender, years of education,history of unprotected sex with non-steady sex part-ner in the last month, number of sex partners in thelast 6 months, frequency of sex with non-steady sexpartner in the last 6 months, and number of any newsex partner(s) in the last 6 months were associatedwith syphilis infection after univariate analysis usingthe chi-squared test. Multivariate logistic regressionanalysis showed that ethnicity (OR, 2.85; 95% CI,1.55-5.25), marriage (OR, 1.94; 95% CI, 1.04-3.62)and receiving money for sex in the last 6 months (OR, ,5.60; 95% CI, 2.65-11.85) were significantly associ-ated with syphilis infection among IDUs.Conclusions: This study found that receiving moneyfor sex in the last 6 months was significantly associ-ated with syphilis prevalence among IDUs. It isrecommended that further health education andintervention campaigns be focused on IDUs to promotesafe sexual practices.目的了解四川省凉山地区静脉吸毒人群梅毒感染情况及相关危险因素。方法于2002年11月8日-29日,以社区为基础开展横断面研究调查静脉吸毒人群的人口学和性行为特征,对采集的血样进行梅毒抗体检测。在社区招募了379个静脉吸毒人员。结果静脉吸毒人群中梅毒感染率为15.3%(58/379)。在单因素卡方分析中,性别、教育年限、近1个月同非主要性伙伴非保护性性行为、近6个月性伙伴人数、近6个月同非主要性伙伴性行为频率、近6个月新的性伙伴人数同梅毒感染有统计学意义。在多因素Logistic回归模型分析中,民族(OR, 2.85; 95% CI, 1.55-5.25), 婚姻(OR, 1.94; 95% CI, 1.04-3.62) 和近6个月以性交为条件接受钱物(OR, 5.60; 95% CI, 2.65-11.85) 同梅毒感染有统计学意义。结论本研究结果显示近6个月以性交为条件接受钱物同梅毒感染有统计学意义。需加强静脉吸毒人群健康教育和行为干预措施来提高其安全性行为。

关 键 词：SYPHILIS STI HIV condom use sexualbehavior IDUS 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]