STI

作品数:795被引量:1410H指数:14
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The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease
《Neural Regeneration Research》2025年第8期2361-2372,共12页Shengyang Zhou Ting Li Wei Zhang Jian Wu Hui Hong Wei Quan Xinyu Qiao Chun Cui Chenmeng Qiao Weijiang Zhao Yanqin Shen 
supported by the National Natural Science Foundation of China,Nos.82171429,81771384;a grant from Wuxi Municipal Health Commission,No.1286010241190480(all to YS)。
Interferon regulatory factor 7 plays a crucial role in the innate immune response.However,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains unknown.Here we report tha...
关键词:cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease NEUROINFLAMMATION Parkinson’s disease RU521 STING type I interferon 
STI技术评价阵发性房颤病人经导管射频消融术前及术后左心房功能和结构的变化
《蚌埠医科大学学报》2025年第3期334-338,共5页吴帅康 王其海 朱坤 杨雯静 
蚌埠医学院自然科学重点研究项目(2020byzd362)。
目的:观察应用二维斑点追踪成像(two-dimensional speckle tracking imaging,STI)测量阵发性心房颤动(atrial fibrillation,AF)病人经导管射频消融术前和术后左心房结构和功能的改变,以评估射频消融术对阵发性AF的临床疗效。方法:选取...
关键词:心房颤动 射频消融术 二维斑点追踪成像 左心房功能 
A new crustin-like gene from the redclaw crayfish Cherax quadricarinatus and its response to decapod iridescent virus 1(DIV1)challenge
《Aquaculture and Fisheries》2025年第1期49-54,共6页Xiaoying Hang Jianbo Zheng Fei Li 
supported by the Key Scientific and Technological Grant of Zhejiang for Breeding New Agricultural Varieties(2021C02069-4-5).
Crustin,a widely-studied antimicrobial peptides(AMPs),has been proven to be involved in mediating innate immune responses against intruding pathogens.In this study,a novel crustin-like gene,Cqcarc1,was characterized f...
关键词:CRUSTIN Cherax quadricarinatus DIV1 Immune defense 
Mannan-decorated STING-activating vaccine carrier for spatial coordinative stimulating antigen-specific immune responses
《Fundamental Research》2025年第1期183-191,共9页Liping Liu Jiayu Zhao Zichao Huang Yudi Xu Hongyu Chen Ruirui Qiao Wantong Song Zhaohui Tang Thomas P.Davis Xuesi Chen 
supported by grants from the National Natural Science Foundation of China(22222509,51973215,52025035,52103194,22105199);the Ministry of Science and Technology of China(2022YFE0110200);Bureau of International Cooperation Chinese Academy of Sciences(121522KYSB20200029);Jilin Province Science and Technology Development Plan(YDZJ202101ZYTS131,20220402037GH);Jilin Provincial International Cooperation Key Laboratory of Biomedical Polymers(20210504001GH);Changchun Science and Technology Development Plan(21ZY09);the Youth Innovation Promotion Association of Chinese Academy of Sciences(2020232).
In recent years,the use of nanotechnologies to improve immunotherapy efficiency has attracted increasing interest in preventive and therapeutic cancer vaccine design.However,current nanocarriers are restricted by diff...
关键词:Cancer immunotherapy Cancer vaccine NANOTECHNOLOGY Drug delivery BIOPOLYMER 
Causal Relationship among Sexually Transmitted Infections, Frequency of Ejaculation and Benign Prostatic Hyperplasia: Emerging Facts or Myths?
《Open Journal of Urology》2025年第2期58-67,共10页Vitalis Obisike Ofuru Ovunda Jack Omodu Ekechi Stella Amadi 
Background: The prevalence of benign prostatic hyperplasia, BPH is increasing in our environment. Besides androgens and age could there be other risk factors? Aim: To investigate the roles of sexually transmitted infe...
关键词:GONORRHEA SYPHILIS CANDIDIASIS STI EJACULATION BPH 
陕西城固柑桔产业链问题透视与智慧化探索
《智慧农业导刊》2025年第3期20-24,共5页贾富基 刘浩 李雨晴 李彬 韩小琴 查博 
2024年西安财经大学校级大学生创新创业训练计划资助项目(X202411560122)。
根据城固柑桔的发展现状,该项目结合投资学、人力资源管理学、新发展理念以及互联网思维等理论和研究方法,探究对于STI模式融入城固柑桔产业创新发展领域的意义和策略。该文在调研的基础上,搭建一个“交互式”的柑桔产业数据交流平台,...
关键词:智慧农业 乡村振兴 城固柑桔 STI模式 增收致富 
One-core neuron deep learning for time series prediction
《National Science Review》2025年第2期309-322,共14页Hao Peng Pei Chen Na Yang Kazuyuki Aihara Rui Liu Luonan Chen 
supported by the National Natural Science Foundation of China(12322119,T2341022,62172164,12271180,T2350003,T2341007,31930022,12426310 and 12131020);the Science and Technology Commission of Shanghai Municipality(23JS1401300);the Japan Science and Technology Agency Moonshot R&D(JPMJMS2021);the Japan Agency for Medical Research and Development(AMED)(JP23dm0307009);the Institute of AI and Beyond at The University of Tokyo,the International Research Center for Neurointelligence(WPI-IRCN);the University of Tokyo Institutes for Advanced Study(UTIAS);the Japan Society for the Promotion of Science(JSPS)Grantsin-Aid for Scientific Research(KAKENHI)(JP20H05921);the Guangdong Basic and Applied Basic Research Foundation(2024A1515011797);the Fundamental Research Funds for the Central Universities(2023ZYGXZR077).
The enormous computational requirements and unsustainable resource consumption associated with massive parameters of large language models and large vision models have given rise to challenging issues.Here,we propose ...
关键词:spatiotemporal information(STI)transformation one-core-neuron(OCN) small model deep learning time-series prediction large model 
STIM Proteins: The Gas and Brake of Calcium Entry in Neurons
《Neuroscience Bulletin》2025年第2期305-325,共21页Ksenia Skobeleva Guanghui Wang Elena Kaznacheyeva 
supported by grants from the Russian Science Foundation(23-44-00054);the National Natural Science Foundation of China(32261133525).
Stromal interaction molecules(STIM)s are Ca^(2+)sensors in internal Ca^(2+)stores of the endoplasmic reticulum.They activate the store-operated Ca^(2+)channels,which are the main source of Ca^(2+)entry in non-excitabl...
关键词:STIM1 STIM2 CALCIUM NEURONS BRAIN Calcium entry Calcium channels 
表儿茶素通过调节cGAS-STING-IRF3通路减轻糖尿病性血管平滑肌衰老
《中医药导报》2025年第1期37-41,共5页张露微 林辉 陈壮 张海琴 童洁 李媛彬 
国家自然科学基金课题(82200333);湖南省自然科学基金课题(2022JJ60077)。
目的:探究表儿茶素对糖尿病小鼠血管平滑肌衰老的作用及表儿茶素在该过程中对cGAS-STINGIRF3信号通路的调节机制。方法:采用腹腔注射链脲佐菌素(STZ)及高糖饲养建立糖尿病小鼠模型,将造模成功小鼠随机分为STZ组、表儿茶素组、二甲双胍组...
关键词:糖尿病 表儿茶素 血管平滑肌衰老 cGAS-STING-IRF3信号通路 小鼠 
Assessment of Salinity Tolerance and Ecotypic Variability in Vicia narbonensis L.:Morphological,Physiological,and Biochemical Responses
《Phyton-International Journal of Experimental Botany》2025年第1期251-267,共17页Hocine Bougrine Salah Hadjout Mohamed Zouidi Abdeldjalil Belkendil Amer Zeghmar Chaouki Boulekdam Walid Ouaret Walid Soufan Fathi Abdellatif Belhouadjeb Amar Mebarkia 
Direction Generale de la Recherche Scientifique et du Developpement Technologique(DGRSDT);Algeria,and the Researchers Supporting Project No.(RSP2025R390),King Saud University,Riyadh,Saudi Arabia.
Salinity stress is a major challenge for global agriculture,particularly in arid and semi-arid regions,limiting plant productivity due to water and soil salinity.These conditions particularly affect countries along th...
关键词:Salinity tolerance Vicia narbonensis morphological traits physiological adaptations biochemical changes salinity tolerance index(STI) 
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