2-羧甲氧基苯甲醛苯甲酰腙及其稀土配合物的合成、表征和抑菌活性  

Synthesis, and Bacteriostatic Activity of 2-(Carboxymethoxyl)benzaldehyde Benzoyl hydrazone and Its Rare Earth Complexes

作　　者：麻宝成[1] 马兴铭[2] 闫兰[1] 杨汝栋[1] 

机构地区：[1]兰州大学化学化工学院,兰州730000 [2]兰州医学院免疫学教研室

出　　处：《应用化学》2004年第8期841-843,共3页Chinese Journal of Applied Chemistry

摘　　要：The 2-(carboxymethoxyl)benzaldehyde benzoyl hydrazone(H 2L) was prepared by condensation of O-formylphenoxy acetic acid with benzoyl hydrazine in ethanol. Eight rare earth complexes with H 2L were synthesized in methanol and characterized by elemental analysis, IR, 1H NMR, EI-MS and molar conductivity measurement. The results indicated the molecular formula of H 2L is C 16H 24N 2O 4 and the composition of rare earth complexes is REL 3·nH 2O(where n=1～2, RE=La, Sm, Eu, Gd, Tb, Dy, Yb and Y). The H 2L as a tridentate ligand coordinates with rare earth ion and forms nine-coordination complexes. The K-B method tests showed the title complexes only have a low bacteriostatic activity against staphylocus auteus, escherichia coil and bacillus subtilis.The 2-(carboxymethoxyl)benzaldehyde benzoyl hydrazone(H 2L) was prepared by condensation of O-formylphenoxy acetic acid with benzoyl hydrazine in ethanol. Eight rare earth complexes with H 2L were synthesized in methanol and characterized by elemental analysis, IR, 1H NMR, EI-MS and molar conductivity measurement. The results indicated the molecular formula of H 2L is C 16H 24N 2O 4 and the composition of rare earth complexes is REL 3·nH 2O(where n=1～2, RE=La, Sm, Eu, Gd, Tb, Dy, Yb and Y). The H 2L as a tridentate ligand coordinates with rare earth ion and forms nine-coordination complexes. The K-B method tests showed the title complexes only have a low bacteriostatic activity against staphylocus auteus, escherichia coil and bacillus subtilis.

关 键 词：稀土 腙 配合物 抑菌活性 

分 类 号：O614.33[理学—无机化学]