脑供血不足患者脂蛋白(a)变化(附33例分析)  

The Changes of Lipoprotein(a) in Cerebral Ischemia Patients

作　　者：钱义兵[1] 曹伟建[1] 丁稚鹰[1] 

机构地区：[1]安徽省省立医院立体定向神经外科研究所生化室,合肥230001

出　　处：《中国血液流变学杂志》2004年第2期219-220,共2页Chinese Journal of Hemorheology

摘　　要：目的　观察 33例经TCD证实的脑供血不足患者血清脂蛋白 (a) [Lp(a) ]浓度变化。方法　采用ELISA双抗体夹心法检测患者组和正常对照组血清Lp(a)浓度。结果　患者组血清LP(a)浓度显著高于正常对照组 (P <0 .0 5 ) ,在性别间差异并无显著性。结论　血清Lp(a)Objective To stuldy the concentration of lipoprotein (a) [Lp(a)] level in serum to 33 patiens with cerebral ischemia proved by Transcranial Doppler (TCD). Methods ELISA diantigen sandwich methods were used for determining Lp(a) level in serum of the patients with cerebral ischemia and in serum of normal controls. Results The concentrations of Lp(a) in patients were obviously higher than those of the normal control( P <0.05). There was no obvious difference between female and male subjects. Conclusion There is closely relationship between the Lp(a) level in serum and cerebrovascular disease induced by atherosclerosis (AS).

关 键 词：脑供血不足 脂蛋白A 动脉粥样硬化 ELISA双抗体夹心法 检测 

分 类 号：R743[医药卫生—神经病学与精神病学]