肝癌患者血清假(拟)胆碱酯酶的测定及其临床意义  

Detection of pseudocholinesterase in patients with liver cancer and its clinical significance

作　　者：赵华[1] 刘琴[1] 王珏[1] 邹学森[1] 刘纬星[2] 

机构地区：[1]江西省肿瘤医院,南昌330029 [2]江西医学院核医学研究室,南昌330006

出　　处：《江西医药》2004年第3期159-160,共2页Jiangxi Medical Journal

摘　　要：目的 探讨肝癌患者血清假(拟)胆碱酯酶(PCHE)活力的变化及其临床意义。方法 采用速率法(双试剂)测定140例原发性肝癌,其中20例转移癌,同时测定白蛋白和总胆汁酸。结果 肝癌组PCHE、ALB均比对照组显著降低,TBA比对照组显著增高。且PCHE与ALB呈正相关,与TBA呈负相关。结论 血清PCHE是反映肝癌患者肝细胞功能受损程度的敏感指标。Objective To investigate the change and clinical significance of serum activity of pseudocholinesterase(PCHE) in patients with liver cancer. Methods Activity of PCHE were detected with Dual-reagent (rate technique) method in 140 patients with primary liver cancer, simultaneously serum concentration of ALB and TBA were measured. Rusults The activity of aerum PCHE and the levels of ALB were singificantly lower in the patients than in the control, the TBA significantly higher. There was negative correlation between the decrease of PCHE and TBA, while positive correlation between PCHE and ALB. Conclution Serum PCHE is sensitive index to reflect damage of liver cell functions in patients with liver cancer.

关 键 词：血清 胆碱酯酶 测定 速率法 白蛋白 总胆汁酸 原发性肝癌 

分 类 号：R735.7[医药卫生—肿瘤]