立体定向射频多靶点联合毁损治疗顽固性精神病  

Stereotactic radiofrequency multi-target lesion for treatment of intractable psychiatric disorder

作　　者：王晓峰[1] 林志国[1] 闫志钧[1] 刘玉芳[1] 陈玥廷[1] 张晶[1] 杨富明[1] 

机构地区：[1]哈尔滨医科大学第一临床医学院X-刀,立体定向功能神经外科,150001

出　　处：《立体定向和功能性神经外科杂志》2004年第3期148-149,155,共3页Chinese Journal of Stereotactic and Functional Neurosurgery

摘　　要：目的　探讨立体定向射频多靶点联合毁损术治疗顽固性精神病的作用。方法　对 30例顽固性精神病患者行CT和MRI引导下立体定向双侧杏仁核和内囊前肢联合毁损 ,症状不缓解病人加行双侧扣带回及双侧尾状核下束毁损术。结果　术后随访 3个月～ 4年 ,有效率为 70 % ,无效率为 30 %。结论　立体定向射频多靶点联合毁损术 ,治疗顽固性精神病是一种较安全。Objective To investigate the effect of stereotactic radiofrequency multi target lesion for treatment of psychiatric disorder.Methods 30 cases of psychiatric disorder were treated by CT or MRI guided stereotactic radiofrequency bilateral amygdatotomy,capsulotomy,and subcaudate tractotomy.Results 30 patients,70% had good outcome and 30% no improvement with follow up 3～48 months after operation.Conclusion Stereotactic radiofrequency lasioning multi target for treatment of Psychiatric disorder is safe and effect.

关 键 词：立体定向 射频毁损 精神病 

分 类 号：R749.05[医药卫生—神经病学与精神病学]